Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 3120..3667 Replicon plasmid unnamed1
Accession NZ_CP109783
Organism Brucella sp. MAB-22

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag OHI65_RS22825 Protein ID WP_151610665.1
Coordinates 3120..3413 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag OHI65_RS22830 Protein ID WP_151610664.1
Coordinates 3413..3667 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OHI65_RS22810 (OHI65_22810) 5..547 - 543 Protein_0 Rieske 2Fe-2S domain-containing protein -
OHI65_RS22815 (OHI65_22815) 673..1590 + 918 WP_151610692.1 LysR family transcriptional regulator -
OHI65_RS22820 (OHI65_22820) 2237..2950 - 714 WP_011983098.1 IS6 family transposase -
OHI65_RS22825 (OHI65_22825) 3120..3413 - 294 WP_151610665.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OHI65_RS22830 (OHI65_22830) 3413..3667 - 255 WP_151610664.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
OHI65_RS22835 (OHI65_22835) 3851..4795 - 945 WP_151610663.1 ornithine cyclodeaminase -
OHI65_RS22840 (OHI65_22840) 4805..5557 - 753 WP_192799582.1 amino acid ABC transporter ATP-binding protein -
OHI65_RS22845 (OHI65_22845) 5581..6507 - 927 WP_151610661.1 amino acid ABC transporter permease -
OHI65_RS22850 (OHI65_22850) 6663..7538 - 876 WP_113534077.1 ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..10913 10913


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-92)

Antitoxin

Antitoxin ParD

(3-70)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11159.93 Da        Isoelectric Point: 6.0740

>T262113 WP_151610665.1 NZ_CP109783:c3413-3120 [Brucella sp. MAB-22]
MEFKLSVLAEDDIIAIAEQGIAMFGPVQAKRYHAELFNTLDLIAKNPQMARAREEISPPVRVHPFKAHLIIYQIEADGTV
FVIRVRHAFEDWVRDPF

Download         Length: 294 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9471.75 Da        Isoelectric Point: 9.6920

>AT262113 WP_151610664.1 NZ_CP109783:c3667-3413 [Brucella sp. MAB-22]
MVTMNVSLPHPMKEWVEAQAKTGRYSNASDYVRDLIRKDQMRSDKIAAMQRFVDEGLQSGPGSRSQDELFAVALANAEKS
LKRN

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References