Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 3120..3667 Replicon plasmid unnamed1
Accession NZ_CP109783
Organism Brucella sp. MAB-22

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag OHI65_RS22825 Protein ID WP_151610665.1
Coordinates 3120..3413 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag OHI65_RS22830 Protein ID WP_151610664.1
Coordinates 3413..3667 (-) Length 85 a.a.

Genomic Context

OHI65_RS22815OHI65_RS22810OHI65_RS22820OHI65_RS22825OHI65_RS22830OHI65_RS22835OHI65_RS22840OHI65_RS22845OHI65_RS22850
Location: 673..1590 (918 bp)
Type: Others
Protein ID: WP_151610692.1
Location: 5..547 (543 bp)
Type: Others
Protein ID: Protein_0
Location: 2237..2950 (714 bp)
Type: Others
Protein ID: WP_011983098.1
Location: 3120..3413 (294 bp)
Type: Toxin
Protein ID: WP_151610665.1
Location: 3413..3667 (255 bp)
Type: Antitoxin
Protein ID: WP_151610664.1
Location: 3851..4795 (945 bp)
Type: Others
Protein ID: WP_151610663.1
Location: 4805..5557 (753 bp)
Type: Others
Protein ID: WP_192799582.1
Location: 5581..6507 (927 bp)
Type: Others
Protein ID: WP_151610661.1
Location: 6663..7538 (876 bp)
Type: Others
Protein ID: WP_113534077.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
OHI65_RS22810 (OHI65_22810)5..547-543Protein_0Rieske 2Fe-2S domain-containing protein-
OHI65_RS22815 (OHI65_22815)673..1590+918WP_151610692.1LysR family transcriptional regulator-
OHI65_RS22820 (OHI65_22820)2237..2950-714WP_011983098.1IS6 family transposase-
OHI65_RS22825 (OHI65_22825)3120..3413-294WP_151610665.1type II toxin-antitoxin system RelE/ParE family toxinToxin
OHI65_RS22830 (OHI65_22830)3413..3667-255WP_151610664.1type II toxin-antitoxin system ParD family antitoxinAntitoxin
OHI65_RS22835 (OHI65_22835)3851..4795-945WP_151610663.1ornithine cyclodeaminase-
OHI65_RS22840 (OHI65_22840)4805..5557-753WP_192799582.1amino acid ABC transporter ATP-binding protein-
OHI65_RS22845 (OHI65_22845)5581..6507-927WP_151610661.1amino acid ABC transporter permease-
OHI65_RS22850 (OHI65_22850)6663..7538-876WP_113534077.1ABC transporter substrate-binding protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..1091310913


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-92)

Antitoxin

Antitoxin ParD

(3-70)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11159.93 Da        Isoelectric Point: 6.0740

>T262113 WP_151610665.1 NZ_CP109783:c3413-3120 [Brucella sp. MAB-22]
MEFKLSVLAEDDIIAIAEQGIAMFGPVQAKRYHAELFNTLDLIAKNPQMARAREEISPPVRVHPFKAHLIIYQIEADGTV
FVIRVRHAFEDWVRDPF

Download         Length: 294 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9471.75 Da        Isoelectric Point: 9.6920

>AT262113 WP_151610664.1 NZ_CP109783:c3667-3413 [Brucella sp. MAB-22]
MVTMNVSLPHPMKEWVEAQAKTGRYSNASDYVRDLIRKDQMRSDKIAAMQRFVDEGLQSGPGSRSQDELFAVALANAEKS
LKRN

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References