Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2434480..2434714 Replicon chromosome
Accession NZ_CP109775
Organism Shigella sonnei strain CIP_106347

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2434481..2434584 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2434480..2434714 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OHN14_RS12530 2430914..2431174 + 261 WP_077447296.1 excisionase -
OHN14_RS12535 2431203..2431657 + 455 Protein_2453 IS1-like element IS1A family transposase -
OHN14_RS12540 2431752..2432980 + 1229 WP_088895425.1 IS3-like element IS2 family transposase -
OHN14_RS12545 2432991..2433236 + 246 Protein_2455 IS1 family transposase -
OHN14_RS12550 2433273..2434349 + 1077 WP_001189101.1 phage integrase Arm DNA-binding domain-containing protein -
- 2434480..2434714 + 235 - - Antitoxin
- 2434481..2434584 - 104 - - Toxin
OHN14_RS12555 2434742..2435083 - 342 WP_000976476.1 YebY family protein -
OHN14_RS12560 2435096..2435968 - 873 WP_000879296.1 copper homeostasis membrane protein CopD -
OHN14_RS12565 2435972..2436346 - 375 WP_000168735.1 CopC domain-containing protein YobA -
OHN14_RS12570 2436485..2436715 + 231 WP_000916763.1 DNA polymerase III subunit theta -
OHN14_RS12575 2436817..2437473 + 657 WP_000011652.1 carbon-nitrogen hydrolase family protein YobB -
OHN14_RS12580 2437497..2438159 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - ipaH9.8 2414818..2440216 25398


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T262103 NZ_CP109775:c2434584-2434481 [Shigella sonnei]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT262103 NZ_CP109775:2434480-2434714 [Shigella sonnei]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References