Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1968151..1968296 Replicon chromosome
Accession NZ_CP109772
Organism Klebsiella pneumoniae strain YZ-58

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1968187..1968289 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1968151..1968296 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M4Z05_RS09950 (M4Z05_09950) 1963281..1965341 + 2061 WP_032420218.1 oligopeptidase B -
M4Z05_RS09955 (M4Z05_09955) 1965345..1966004 - 660 WP_002911407.1 exodeoxyribonuclease X -
M4Z05_RS09960 (M4Z05_09960) 1966083..1966313 - 231 WP_002911406.1 DNA polymerase III subunit theta -
M4Z05_RS09965 (M4Z05_09965) 1966426..1966800 + 375 WP_004151448.1 CopC domain-containing protein YobA -
M4Z05_RS09970 (M4Z05_09970) 1966804..1967673 + 870 WP_032420215.1 copper homeostasis membrane protein CopD -
M4Z05_RS09975 (M4Z05_09975) 1967690..1968028 + 339 WP_002911404.1 YebY family protein -
- 1968151..1968296 - 146 - - Antitoxin
- 1968187..1968289 + 103 - - Toxin
M4Z05_RS09980 (M4Z05_09980) 1968664..1968807 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
M4Z05_RS09985 (M4Z05_09985) 1968912..1969880 - 969 WP_004151446.1 VirK/YbjX family protein -
M4Z05_RS09990 (M4Z05_09990) 1970037..1970690 + 654 WP_064149174.1 protein-serine/threonine phosphatase -
M4Z05_RS09995 (M4Z05_09995) 1970687..1970878 - 192 WP_002911395.1 YebW family protein -
M4Z05_RS10000 (M4Z05_10000) 1970976..1971215 - 240 WP_002911393.1 YebV family protein -
M4Z05_RS10005 (M4Z05_10005) 1971331..1972764 - 1434 WP_064149175.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T262085 NZ_CP109772:1968187-1968289 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT262085 NZ_CP109772:c1968296-1968151 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References