Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 1474497..1475413 Replicon chromosome
Accession NC_017047
Organism Rahnella aquatilis HX2

Toxin (Protein)


Gene name - Uniprot ID H8NRM1
Locus tag Q7S_RS06765 Protein ID WP_013574722.1
Coordinates 1474497..1474955 (-) Length 153 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID H2IQN3
Locus tag Q7S_RS06770 Protein ID WP_013574723.1
Coordinates 1474952..1475413 (-) Length 154 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Q7S_RS06740 1470123..1471808 + 1686 WP_013574717.1 choline dehydrogenase -
Q7S_RS06745 1471899..1472357 + 459 WP_013574718.1 GNAT family N-acetyltransferase -
Q7S_RS06750 1472545..1473477 - 933 WP_041673052.1 LysR family transcriptional regulator -
Q7S_RS06755 1473579..1474013 + 435 WP_013574720.1 DMT family transporter -
Q7S_RS06760 1474017..1474469 + 453 WP_015689555.1 DMT family transporter -
Q7S_RS06765 1474497..1474955 - 459 WP_013574722.1 RES family NAD+ phosphorylase Toxin
Q7S_RS06770 1474952..1475413 - 462 WP_013574723.1 DUF2384 domain-containing protein Antitoxin
Q7S_RS06775 1475764..1476651 + 888 WP_015689556.1 nucleoside-specific channel-forming protein Tsx -
Q7S_RS06780 1476838..1478433 + 1596 WP_013574725.1 ABC-F family ATPase -
Q7S_RS06785 1478627..1479388 - 762 WP_015689557.1 molybdopterin-synthase adenylyltransferase MoeB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(2-136)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(34-95)


Sequences

Toxin        


Download         Length: 153 a.a.        Molecular weight: 16974.55 Da        Isoelectric Point: 4.7091

>T26208 WP_013574722.1 NC_017047:c1474955-1474497 [Rahnella aquatilis HX2]
MKLFRIVQTRHLATAWSGAGAQLYGGRWNPPGRPVVYVTTSISLAILEILVHLQNSMLMRSYTLLSIEVPEELLDTLEVS
ELAADWRSASVPDSTQRQGDVWLAEGEYVGLKVPSVIVPSEYNVLLNPLHPAFADLLSSVEREPMMFDPRLQ

Download         Length: 459 bp

>T26208 NC_017047:c1474955-1474497 [Rahnella aquatilis HX2]
TTGAAGCTGTTTCGTATCGTGCAGACCCGTCATCTGGCGACAGCCTGGTCGGGAGCCGGCGCGCAACTTTATGGCGGTCG
CTGGAATCCGCCAGGCAGGCCGGTCGTCTATGTCACCACCAGCATCTCACTGGCTATCCTGGAAATTCTGGTGCATTTGC
AAAACAGCATGTTGATGCGTTCCTATACCTTGCTGAGTATTGAGGTGCCAGAGGAACTGCTGGATACGCTGGAAGTTTCA
GAGCTTGCCGCCGACTGGCGAAGCGCATCAGTGCCTGACAGCACTCAACGTCAGGGTGACGTCTGGCTTGCAGAAGGTGA
ATATGTCGGGCTGAAAGTGCCGTCAGTGATTGTGCCGTCGGAATACAACGTATTACTTAATCCGCTACACCCGGCTTTTG
CCGATTTACTGAGTTCAGTAGAACGCGAGCCCATGATGTTTGACCCGCGCCTGCAATAA

Antitoxin


Download         Length: 154 a.a.        Molecular weight: 16505.80 Da        Isoelectric Point: 7.0196

>AT26208 WP_013574723.1 NC_017047:c1475413-1474952 [Rahnella aquatilis HX2]
MNSKITGLSSSSVQDSATPLWQSAGLPASSGISLINAIQKGFPVDSISRLNTELGWPKMVLLEIMGINERNYARRKAGNG
LLKSEESERVARLVRIVDAATDLFEGDRVSALEWFTRPAPALDGSRPLELLSSEAGAVEVSRLIGRLQHGVFS

Download         Length: 462 bp

>AT26208 NC_017047:c1475413-1474952 [Rahnella aquatilis HX2]
ATGAATTCAAAAATTACCGGGCTGTCTTCCAGCTCTGTGCAAGATTCTGCAACGCCGCTTTGGCAATCTGCGGGCCTTCC
CGCAAGCAGCGGAATCAGTTTGATAAATGCCATACAAAAGGGATTTCCTGTTGATAGTATCAGCCGTCTTAATACTGAGC
TGGGATGGCCAAAAATGGTGTTACTGGAAATCATGGGCATTAACGAACGCAACTATGCCCGGCGTAAAGCCGGGAACGGA
TTGCTAAAAAGTGAAGAGAGTGAACGTGTGGCGCGACTGGTTCGCATCGTGGATGCCGCAACTGATTTGTTCGAAGGGGA
TCGTGTCTCGGCGCTCGAATGGTTCACCCGCCCTGCTCCGGCACTGGATGGTTCACGTCCGCTGGAACTGCTGTCTTCTG
AAGCGGGTGCTGTGGAAGTCAGCCGCCTGATTGGTCGTCTCCAGCACGGTGTTTTCAGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB H8NRM1

Antitoxin

Source ID Structure
AlphaFold DB A0A0H3F7Y1

References