Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relE-yefM/Txe-RelB |
Location | 190004..190533 | Replicon | chromosome |
Accession | NZ_CP109758 | ||
Organism | Enterococcus faecium strain XJ78NG |
Toxin (Protein)
Gene name | relE | Uniprot ID | C9B8W9 |
Locus tag | OH471_RS00950 | Protein ID | WP_002294198.1 |
Coordinates | 190267..190533 (+) | Length | 89 a.a. |
Antitoxin (Protein)
Gene name | yefM | Uniprot ID | C9B8W8 |
Locus tag | OH471_RS00945 | Protein ID | WP_002294199.1 |
Coordinates | 190004..190267 (+) | Length | 88 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
OH471_RS00930 (OH471_00930) | 187379..189202 | + | 1824 | WP_002294202.1 | APC family permease | - |
OH471_RS00935 (OH471_00935) | 189344..189529 | - | 186 | WP_002294201.1 | hypothetical protein | - |
OH471_RS00940 (OH471_00940) | 189536..189664 | + | 129 | WP_002294200.1 | hypothetical protein | - |
OH471_RS00945 (OH471_00945) | 190004..190267 | + | 264 | WP_002294199.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
OH471_RS00950 (OH471_00950) | 190267..190533 | + | 267 | WP_002294198.1 | Txe/YoeB family addiction module toxin | Toxin |
OH471_RS00955 (OH471_00955) | 190735..191223 | + | 489 | WP_002294196.1 | mannosyl-glycoprotein endo-beta-N-acetylglucosamidase | - |
OH471_RS00960 (OH471_00960) | 191765..192436 | - | 672 | WP_002319469.1 | ABC transporter permease | - |
OH471_RS00965 (OH471_00965) | 192433..193350 | - | 918 | WP_002294193.1 | osmoprotectant ABC transporter substrate-binding protein | - |
OH471_RS00970 (OH471_00970) | 193347..193988 | - | 642 | WP_002293405.1 | ABC transporter permease | - |
OH471_RS00975 (OH471_00975) | 193992..195167 | - | 1176 | WP_002294192.1 | betaine/proline/choline family ABC transporter ATP-binding protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A829FMA0 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A828ZU84 |