Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/ElaA-DUF1778
Location 135648..136387 Replicon plasmid p2017-45-131-01A_1
Accession NZ_CP109755
Organism Enterobacter roggenkampii strain 2017-45-131-01A

Toxin (Protein)


Gene name tacT Uniprot ID A0A9E6WPH7
Locus tag OI984_RS25205 Protein ID WP_013087269.1
Coordinates 135902..136387 (+) Length 162 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID A0A9E6WPN8
Locus tag OI984_RS25200 Protein ID WP_007869691.1
Coordinates 135648..135914 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OI984_RS25180 (OI984_25180) 131535..131777 + 243 WP_008502222.1 hypothetical protein -
OI984_RS25185 (OI984_25185) 132111..132878 + 768 WP_008502221.1 TraX family protein -
OI984_RS25190 (OI984_25190) 132900..133199 - 300 WP_226840878.1 DUF2767 family protein -
OI984_RS25195 (OI984_25195) 133982..134995 - 1014 WP_039265242.1 plasmid replication initiator RepA -
OI984_RS25200 (OI984_25200) 135648..135914 + 267 WP_007869691.1 DUF1778 domain-containing protein Antitoxin
OI984_RS25205 (OI984_25205) 135902..136387 + 486 WP_013087269.1 GNAT family N-acetyltransferase Toxin
OI984_RS25210 (OI984_25210) 136594..137939 + 1346 Protein_157 ISNCY family transposase -
OI984_RS25215 (OI984_25215) 138034..138261 - 228 Protein_158 transposase -
OI984_RS25220 (OI984_25220) 138543..139139 - 597 Protein_159 IS3-like element ISEc52 family transposase -
OI984_RS25225 (OI984_25225) 139127..139207 + 81 Protein_160 hypothetical protein -
OI984_RS25230 (OI984_25230) 139204..139530 + 327 Protein_161 helix-turn-helix domain-containing protein -
OI984_RS25235 (OI984_25235) 139680..140660 - 981 WP_000019445.1 IS5-like element ISKpn26 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - cheD 1..197426 197426


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(45-146)

Antitoxin

Vibrio phage ICP1, Orf50

(6-82)


Sequences

Toxin        


Download         Length: 162 a.a.        Molecular weight: 17736.45 Da        Isoelectric Point: 9.5181

>T262075 WP_013087269.1 NZ_CP109755:135902-136387 [Enterobacter roggenkampii]
VGRVTAPEPLSSSHQLAEFVSGEAVLDDWLKQRGLKNQALGAARTFVVCKRDTKQVVGFYSLATGSVNHVEAMGSLRRNM
PDPIPVIILARLAVDVSYRGQGLGADLLHDAVLRCYRVAENIGVRAIMVHALTEEAKNFYLHHGFKASQTQERTLFLKLP
Q

Download         Length: 486 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10080.46 Da        Isoelectric Point: 4.3837

>AT262075 WP_007869691.1 NZ_CP109755:135648-135914 [Enterobacter roggenkampii]
MKSDVQLNLRAKESQRALIDAAAEILHKSRTDFILEMACQAAENVILDRRVFNFNDEQYAEFIDMLDAPVSDEAAIDKLL
ARKPQWDV

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References