Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /RES-TIGR02293 |
| Location | 972276..973189 | Replicon | chromosome |
| Accession | NZ_CP109753 | ||
| Organism | Enterobacter roggenkampii strain 2017-45-131-01A | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | OI984_RS04880 | Protein ID | WP_045352049.1 |
| Coordinates | 972716..973189 (+) | Length | 158 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | OI984_RS04875 | Protein ID | WP_045352048.1 |
| Coordinates | 972276..972719 (+) | Length | 148 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| OI984_RS04860 (OI984_04865) | 967720..969441 | + | 1722 | WP_021240888.1 | cysteine/glutathione ABC transporter ATP-binding protein/permease CydC | - |
| OI984_RS04865 (OI984_04870) | 969487..970191 | + | 705 | WP_008499991.1 | leucyl/phenylalanyl-tRNA--protein transferase | - |
| OI984_RS04870 (OI984_04875) | 970476..970694 | + | 219 | WP_002211347.1 | translation initiation factor IF-1 | - |
| OI984_RS04875 (OI984_04880) | 972276..972719 | + | 444 | WP_045352048.1 | DUF2384 domain-containing protein | Antitoxin |
| OI984_RS04880 (OI984_04885) | 972716..973189 | + | 474 | WP_045352049.1 | RES family NAD+ phosphorylase | Toxin |
| OI984_RS04885 (OI984_04890) | 973211..973768 | - | 558 | WP_045352052.1 | type I-F CRISPR-associated endoribonuclease Cas6/Csy4 | - |
| OI984_RS04890 (OI984_04895) | 973778..974776 | - | 999 | WP_045352054.1 | type I-F CRISPR-associated protein Csy3 | - |
| OI984_RS04895 (OI984_04900) | 974790..975725 | - | 936 | WP_045352056.1 | type I-F CRISPR-associated protein Csy2 | - |
| OI984_RS04900 (OI984_04905) | 975722..977032 | - | 1311 | WP_045352058.1 | type I-F CRISPR-associated protein Csy1 | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 158 a.a. Molecular weight: 17599.88 Da Isoelectric Point: 5.0701
>T262065 WP_045352049.1 NZ_CP109753:972716-973189 [Enterobacter roggenkampii]
MIFYRLVTGRYASEAWSGSGANQYGGRWNHKGHPAVYVSTSISLASLEILVHVRKDTVLNQYQLFSIDIPDDQIDYLDKA
WLPEDWQENPAPVSTMDLGTGWLQANSALALILPSYIIPYENNAILNPLHPAFHSALNSVQQLPFIFDTRLAEKTAP
MIFYRLVTGRYASEAWSGSGANQYGGRWNHKGHPAVYVSTSISLASLEILVHVRKDTVLNQYQLFSIDIPDDQIDYLDKA
WLPEDWQENPAPVSTMDLGTGWLQANSALALILPSYIIPYENNAILNPLHPAFHSALNSVQQLPFIFDTRLAEKTAP
Download Length: 474 bp
Antitoxin
Download Length: 148 a.a. Molecular weight: 16384.74 Da Isoelectric Point: 7.2062
>AT262065 WP_045352048.1 NZ_CP109753:972276-972719 [Enterobacter roggenkampii]
MRTWIPAQKPADNALWRYAGLPANRGMRLIEFLNQGLPVSVLDNIHEWTSMSKADILRVTGINERNVARRKSAGRTLTPD
ESERVARFVRVLDAAVDYFGSKEEAWTWLQAPVRGLGNMAPVDLIATETGALEVTDLIGRLEHGVFA
MRTWIPAQKPADNALWRYAGLPANRGMRLIEFLNQGLPVSVLDNIHEWTSMSKADILRVTGINERNVARRKSAGRTLTPD
ESERVARFVRVLDAAVDYFGSKEEAWTWLQAPVRGLGNMAPVDLIATETGALEVTDLIGRLEHGVFA
Download Length: 444 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|