Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2085591..2086245 Replicon chromosome
Accession NZ_CP109744
Organism Citrobacter portucalensis strain 2017-45-163

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag OI981_RS10030 Protein ID WP_003825515.1
Coordinates 2085838..2086245 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag OI981_RS10025 Protein ID WP_003825514.1
Coordinates 2085591..2085857 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OI981_RS10000 (OI981_09995) 2080746..2082179 - 1434 WP_060683276.1 6-phospho-beta-glucosidase BglA -
OI981_RS10005 (OI981_10000) 2082300..2083028 - 729 WP_008785744.1 MurR/RpiR family transcriptional regulator -
OI981_RS10010 (OI981_10005) 2083081..2083392 + 312 WP_048225466.1 N(4)-acetylcytidine aminohydrolase -
OI981_RS10015 (OI981_10010) 2083556..2084218 + 663 WP_060683277.1 hemolysin III family protein -
OI981_RS10020 (OI981_10015) 2084350..2085333 - 984 WP_060683278.1 tRNA-modifying protein YgfZ -
OI981_RS10025 (OI981_10020) 2085591..2085857 + 267 WP_003825514.1 FAD assembly factor SdhE Antitoxin
OI981_RS10030 (OI981_10025) 2085838..2086245 + 408 WP_003825515.1 protein YgfX Toxin
OI981_RS10035 (OI981_10030) 2086347..2086868 - 522 WP_003026933.1 flavodoxin FldB -
OI981_RS10040 (OI981_10035) 2086982..2087878 + 897 WP_003825519.1 site-specific tyrosine recombinase XerD -
OI981_RS10045 (OI981_10040) 2087902..2088612 + 711 WP_060683280.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
OI981_RS10050 (OI981_10045) 2088618..2090351 + 1734 WP_048215591.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15882.76 Da        Isoelectric Point: 11.3523

>T262053 WP_003825515.1 NZ_CP109744:2085838-2086245 [Citrobacter portucalensis]
VVQWQSDLRVSWRAQWLSLLIHGLVAVFILLMPWPLSYTPLWLVLLSLVVFDSVRSQRRINACQGEIRLLMDGRLRWQGQ
EWSIVSAPWMVKTGMMLRLRSDAGKRQHLWLAADSMDDAEWRDLRRLMLQKAKQG

Download         Length: 408 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10615.14 Da        Isoelectric Point: 5.1700

>AT262053 WP_003825514.1 NZ_CP109744:2085591-2085857 [Citrobacter portucalensis]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFIRLLECDDPDLFNWLMNHGKPADEQLEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References