Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 3673800..3674431 Replicon chromosome
Accession NZ_CP109739
Organism Serratia nevei strain 2017-45-174

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag OI978_RS17575 Protein ID WP_055313518.1
Coordinates 3674033..3674431 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A0G3SVC2
Locus tag OI978_RS17570 Protein ID WP_047730457.1
Coordinates 3673800..3674033 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OI978_RS17545 (OI978_17540) 3668952..3670568 + 1617 WP_284594404.1 methyl-accepting chemotaxis protein -
OI978_RS17550 (OI978_17545) 3670606..3671478 + 873 WP_025159837.1 protein-glutamate O-methyltransferase CheR -
OI978_RS17555 (OI978_17550) 3671478..3672527 + 1050 WP_284594405.1 chemotaxis response regulator protein-glutamate methylesterase -
OI978_RS17560 (OI978_17555) 3672630..3673019 + 390 WP_004934862.1 chemotaxis response regulator CheY -
OI978_RS17565 (OI978_17560) 3673030..3673674 + 645 WP_004934858.1 protein phosphatase CheZ -
OI978_RS17570 (OI978_17565) 3673800..3674033 + 234 WP_047730457.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
OI978_RS17575 (OI978_17570) 3674033..3674431 + 399 WP_055313518.1 type II toxin-antitoxin system VapC family toxin Toxin
OI978_RS17580 (OI978_17575) 3674558..3675709 + 1152 WP_047730459.1 flagellar biosynthesis protein FlhB -
OI978_RS17585 (OI978_17580) 3675702..3677780 + 2079 WP_038876828.1 flagellar biosynthesis protein FlhA -
OI978_RS17590 (OI978_17585) 3677780..3678184 + 405 WP_047730460.1 flagellar protein FlhE -
OI978_RS17595 (OI978_17590) 3678513..3679328 + 816 WP_055316342.1 5'-nucleotidase, lipoprotein e(P4) family -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-124)

Antitoxin

SpoVT-AbrB domain

(7-45)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14932.09 Da        Isoelectric Point: 7.4664

>T262042 WP_055313518.1 NZ_CP109739:3674033-3674431 [Serratia nevei]
MFSHMLDTNIVIYVIKRRPLEVLEAFNRYAGKMVISSITYGELVHGVENSARPAVNARVVEDFVSRLDILDYSAKAASHY
GNIRAVLERQGTPIGVNDLHIAGHARSEGLILVTNNRREFERVEGLRLENWL

Download         Length: 399 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8841.85 Da        Isoelectric Point: 4.7815

>AT262042 WP_047730457.1 NZ_CP109739:3673800-3674033 [Serratia nevei]
MALGSVFTNNRTQAVRLPAEVRFPDTVSKVTVRVVGKERILAPLENTWDSFFCAENEVSDDFLNERAGQHQREREDF

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0G3SVC2

References