Detailed information of TA system TA026204

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-DnaT
• Location: 27539..28061
• Replicon: chromosome
• Accession: NC_017047
• Organism: Rahnella aquatilis HX2

Toxin (Protein)

• Gene name: relE
• Uniprot ID: H8NLY9
• Locus tag: Q7S_RS00125
• Protein ID: WP_013573377.1
• Coordinates: 27777..28061 (+)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: H8NLY8
• Locus tag: Q7S_RS00120
• Protein ID: WP_013573376.1
• Coordinates: 27539..27787 (+)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
Q7S_RS00100	23282..24028	-	747	WP_014411433.1	OmpA family lipoprotein	-
Q7S_RS00105	24250..24693	-	444	WP_013573373.1	N-acetyltransferase	-
Q7S_RS00110	24690..25262	-	573	WP_013573374.1	DNA-3-methyladenine glycosylase I	-
Q7S_RS00115	25454..27460	+	2007	WP_013573375.1	autotransporter domain-containing esterase	-
Q7S_RS00120	27539..27787	+	249	WP_013573376.1	plasmid stabilization protein	Antitoxin
Q7S_RS00125	27777..28061	+	285	WP_013573377.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
Q7S_RS00130	28183..29097	+	915	WP_014333298.1	glycine--tRNA ligase subunit alpha	-
Q7S_RS00135	29107..31176	+	2070	WP_013573379.1	glycine--tRNA ligase subunit beta	-
Q7S_RS00140	31387..32109	+	723	WP_013573380.1	DUF3053 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-82)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 10954.92 Da
• Isoelectric Point: 10.5358

>T26204 WP_013573377.1 NC_017047:27777-28061 [Rahnella aquatilis HX2]
MTYKLNFFKSALKEWKALAPTIKEQFKKKLAERLENPHVVSARLCGPKNNRYKIKLKSLGYRLVYQVEDQEIIVTVVAVG
KREGNEAYKLAEKR

Nucleotide

• Length: 285 bp

>T26204 NC_017047:27777-28061 [Rahnella aquatilis HX2]
ATGACTTATAAACTCAATTTTTTCAAATCAGCTTTAAAAGAATGGAAAGCACTTGCCCCAACGATCAAGGAGCAATTTAA
AAAGAAACTGGCCGAGCGGCTGGAGAATCCTCACGTGGTTTCTGCCCGCTTATGTGGCCCCAAAAATAACCGCTATAAAA
TCAAATTAAAGAGTCTTGGTTATCGCCTGGTGTATCAGGTAGAAGATCAGGAAATCATCGTGACCGTTGTCGCGGTGGGT
AAACGCGAAGGCAACGAAGCGTATAAACTGGCTGAGAAGCGCTAA

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9155.35 Da
• Isoelectric Point: 3.9951

>AT26204 WP_013573376.1 NC_017047:27539-27787 [Rahnella aquatilis HX2]
MPFEILTSSAASITELKRDPMGTFSAGEGEAVAILNRNEPAFYCVPPDVYAYFLSLAEDVELNRIMDARQGEERIRLTLD
DL

Nucleotide

• Length: 249 bp

>AT26204 NC_017047:27539-27787 [Rahnella aquatilis HX2]
ATGCCGTTTGAAATACTCACTTCCTCAGCCGCCAGTATTACTGAACTAAAACGCGACCCGATGGGAACATTTAGTGCAGG
CGAAGGCGAAGCGGTGGCGATACTCAATCGTAACGAGCCCGCTTTTTATTGCGTTCCGCCCGATGTTTACGCCTATTTTC
TGAGTCTTGCAGAAGACGTTGAATTGAACCGCATAATGGATGCGCGGCAGGGTGAAGAAAGGATAAGGCTGACACTGGAT
GACTTATAA

Structures

Toxin

• AlphaFold DB: H8NLY9

Antitoxin

• AlphaFold DB: H8NLY8