Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2398216..2398885 Replicon chromosome
Accession NZ_CP109739
Organism Serratia nevei strain 2017-45-174

Toxin (Protein)


Gene name cptA Uniprot ID A0A5P6GZ53
Locus tag OI978_RS11410 Protein ID WP_047729923.1
Coordinates 2398463..2398885 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A8B4GS04
Locus tag OI978_RS11405 Protein ID WP_019455657.1
Coordinates 2398216..2398482 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OI978_RS11380 (OI978_11375) 2393791..2394717 + 927 WP_047729921.1 ribokinase -
OI978_RS11385 (OI978_11380) 2394750..2395358 - 609 WP_025304127.1 HD domain-containing protein -
OI978_RS11390 (OI978_11385) 2395542..2396216 + 675 WP_038871224.1 hemolysin III family protein -
OI978_RS11395 (OI978_11390) 2396367..2396864 + 498 WP_038871226.1 DUF2165 domain-containing protein -
OI978_RS11400 (OI978_11395) 2396903..2397895 - 993 WP_047729922.1 tRNA-modifying protein YgfZ -
OI978_RS11405 (OI978_11400) 2398216..2398482 + 267 WP_019455657.1 FAD assembly factor SdhE Antitoxin
OI978_RS11410 (OI978_11405) 2398463..2398885 + 423 WP_047729923.1 protein YgfX Toxin
OI978_RS11415 (OI978_11410) 2398885..2399580 + 696 WP_055316660.1 two-component system response regulator CreB -
OI978_RS11420 (OI978_11415) 2399577..2400995 + 1419 WP_055316662.1 two-component system sensor histidine kinase CreC -
OI978_RS11425 (OI978_11420) 2401076..2402440 + 1365 WP_047729926.1 cell envelope integrity protein CreD -
OI978_RS11430 (OI978_11425) 2402477..2402995 - 519 WP_038871234.1 flavodoxin FldB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16500.57 Da        Isoelectric Point: 10.8114

>T262038 WP_047729923.1 NZ_CP109739:2398463-2398885 [Serratia nevei]
VAQWRCDIRISWRTQLFSLLTHGVLILLILISPWPEGFGPLWLVLLTLVVFQCIRSQKRIAAVQGELRLLADRRFSWHGR
EWRLAKKPWMPGYGMLLTLQPTEGKKRRRLWLASDCMSKEEWRHLRQLLLYPPVGDGEEA

Download         Length: 423 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10417.91 Da        Isoelectric Point: 4.7921

>AT262038 WP_019455657.1 NZ_CP109739:2398216-2398482 [Serratia nevei]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLNDADKALFIRLLECDDPDLFNWLMNHGAPQDSELQRMVTLIQTRN
KDRGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A5P6GZ53

Antitoxin

Source ID Structure
AlphaFold DB A0A8B4GS04

References