Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 4209801..4210458 Replicon chromosome
Accession NZ_CP109733
Organism Providencia thailandensis strain 2017-45-35

Toxin (Protein)


Gene name cptA Uniprot ID A0A7T1H2A7
Locus tag OI982_RS19700 Protein ID WP_036941148.1
Coordinates 4210048..4210458 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID B2Q1I8
Locus tag OI982_RS19695 Protein ID WP_004921708.1
Coordinates 4209801..4210067 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OI982_RS19680 (OI982_19850) 4204832..4207708 + 2877 WP_141173656.1 aminomethyl-transferring glycine dehydrogenase -
OI982_RS19685 (OI982_19855) 4207927..4208547 - 621 WP_004921714.1 HD domain-containing protein -
OI982_RS19690 (OI982_19860) 4208559..4209548 - 990 WP_141173655.1 tRNA-modifying protein YgfZ -
OI982_RS19695 (OI982_19865) 4209801..4210067 + 267 WP_004921708.1 FAD assembly factor SdhE Antitoxin
OI982_RS19700 (OI982_19870) 4210048..4210458 + 411 WP_036941148.1 protein YgfX Toxin
OI982_RS19705 (OI982_19875) 4210504..4211022 - 519 WP_014656387.1 flavodoxin FldB -
OI982_RS19710 (OI982_19880) 4211185..4212108 + 924 WP_141173654.1 site-specific tyrosine recombinase XerD -
OI982_RS19715 (OI982_19885) 4212128..4212832 + 705 WP_141173653.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
OI982_RS19720 (OI982_19890) 4212838..4214571 + 1734 WP_004921693.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-133)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15289.15 Da        Isoelectric Point: 10.8779

>T262031 WP_036941148.1 NZ_CP109733:4210048-4210458 [Providencia thailandensis]
VVLWKSNLSISWKTQLFSTCAHGVVGFILLVAPWAPGNSMVWLPLLVIVIASWAKSQKSISKIKGTAVLVNGNKVQWKKN
EWSIVKQPWCSRVGVLLTLSALQGKPQKIRLWVAKDALSEESWRNLNQLLLQYPDI

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10576.10 Da        Isoelectric Point: 4.9104

>AT262031 WP_004921708.1 NZ_CP109733:4209801-4210067 [Providencia thailandensis]
MDIENKARIHWACRRGMRELDISIMPFFEYEYEGLSDKDKRTFVRLLECADPDLFNWLMNHGRPDDDELFGMVKLIQERN
KNRGPVEI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7T1H2A7

Antitoxin

Source ID Structure
AlphaFold DB A0A140NIX0

References