Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/ElaA-DUF1778
Location 77525..78264 Replicon plasmid p2017-45-51-04-01_2
Accession NZ_CP109731
Organism Enterobacter roggenkampii strain 2017-45-51-04-01

Toxin (Protein)


Gene name tacT Uniprot ID A0A9E6WPH7
Locus tag OI980_RS26940 Protein ID WP_013087269.1
Coordinates 77525..78010 (-) Length 162 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID A0A9E6WPN8
Locus tag OI980_RS26945 Protein ID WP_007869691.1
Coordinates 77998..78264 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OI980_RS26920 (OI980_26910) 72577..73980 - 1404 WP_001567368.1 ISNCY-like element ISKpn21 family transposase -
OI980_RS26925 (OI980_26915) 74222..75190 - 969 WP_022652343.1 IS5-like element IS903B family transposase -
OI980_RS26930 (OI980_26920) 75265..75897 + 633 WP_284608208.1 hypothetical protein -
OI980_RS26935 (OI980_26925) 75926..77329 - 1404 WP_001567368.1 ISNCY-like element ISKpn21 family transposase -
OI980_RS26940 (OI980_26930) 77525..78010 - 486 WP_013087269.1 GNAT family N-acetyltransferase Toxin
OI980_RS26945 (OI980_26935) 77998..78264 - 267 WP_007869691.1 DUF1778 domain-containing protein Antitoxin
OI980_RS26950 (OI980_26940) 78917..79930 + 1014 WP_039265242.1 plasmid replication initiator RepA -
OI980_RS26955 (OI980_26945) 80713..81012 + 300 WP_226840878.1 DUF2767 family protein -
OI980_RS26960 (OI980_26950) 81034..81801 - 768 WP_008502221.1 TraX family protein -
OI980_RS26965 (OI980_26955) 82135..82377 - 243 WP_008502222.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - cheD 1..184755 184755


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(45-146)

Antitoxin

Vibrio phage ICP1, Orf50

(6-82)


Sequences

Toxin        


Download         Length: 162 a.a.        Molecular weight: 17736.45 Da        Isoelectric Point: 9.5181

>T262028 WP_013087269.1 NZ_CP109731:c78010-77525 [Enterobacter roggenkampii]
VGRVTAPEPLSSSHQLAEFVSGEAVLDDWLKQRGLKNQALGAARTFVVCKRDTKQVVGFYSLATGSVNHVEAMGSLRRNM
PDPIPVIILARLAVDVSYRGQGLGADLLHDAVLRCYRVAENIGVRAIMVHALTEEAKNFYLHHGFKASQTQERTLFLKLP
Q

Download         Length: 486 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10080.46 Da        Isoelectric Point: 4.3837

>AT262028 WP_007869691.1 NZ_CP109731:c78264-77998 [Enterobacter roggenkampii]
MKSDVQLNLRAKESQRALIDAAAEILHKSRTDFILEMACQAAENVILDRRVFNFNDEQYAEFIDMLDAPVSDEAAIDKLL
ARKPQWDV

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References