Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 2139875..2140788 Replicon chromosome
Accession NZ_CP109727
Organism Enterobacter roggenkampii strain 2017-45-51-04-01

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag OI980_RS10225 Protein ID WP_045352049.1
Coordinates 2139875..2140348 (-) Length 158 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag OI980_RS10230 Protein ID WP_045352048.1
Coordinates 2140345..2140788 (-) Length 148 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OI980_RS10205 (OI980_10200) 2136032..2137342 + 1311 WP_045352058.1 type I-F CRISPR-associated protein Csy1 -
OI980_RS10210 (OI980_10205) 2137339..2138274 + 936 WP_045352056.1 type I-F CRISPR-associated protein Csy2 -
OI980_RS10215 (OI980_10210) 2138288..2139286 + 999 WP_045352054.1 type I-F CRISPR-associated protein Csy3 -
OI980_RS10220 (OI980_10215) 2139296..2139853 + 558 WP_045352052.1 type I-F CRISPR-associated endoribonuclease Cas6/Csy4 -
OI980_RS10225 (OI980_10220) 2139875..2140348 - 474 WP_045352049.1 RES family NAD+ phosphorylase Toxin
OI980_RS10230 (OI980_10225) 2140345..2140788 - 444 WP_045352048.1 DUF2384 domain-containing protein Antitoxin
OI980_RS10235 (OI980_10230) 2142370..2142588 - 219 WP_002211347.1 translation initiation factor IF-1 -
OI980_RS10240 (OI980_10235) 2142873..2143577 - 705 WP_008499991.1 leucyl/phenylalanyl-tRNA--protein transferase -
OI980_RS10245 (OI980_10240) 2143623..2145344 - 1722 WP_021240888.1 cysteine/glutathione ABC transporter ATP-binding protein/permease CydC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-148)

Antitoxin

Antitoxin Xre

(15-147)


Sequences

Toxin        


Download         Length: 158 a.a.        Molecular weight: 17599.88 Da        Isoelectric Point: 5.0701

>T262019 WP_045352049.1 NZ_CP109727:c2140348-2139875 [Enterobacter roggenkampii]
MIFYRLVTGRYASEAWSGSGANQYGGRWNHKGHPAVYVSTSISLASLEILVHVRKDTVLNQYQLFSIDIPDDQIDYLDKA
WLPEDWQENPAPVSTMDLGTGWLQANSALALILPSYIIPYENNAILNPLHPAFHSALNSVQQLPFIFDTRLAEKTAP

Download         Length: 474 bp

Antitoxin


Download         Length: 148 a.a.        Molecular weight: 16384.74 Da        Isoelectric Point: 7.2062

>AT262019 WP_045352048.1 NZ_CP109727:c2140788-2140345 [Enterobacter roggenkampii]
MRTWIPAQKPADNALWRYAGLPANRGMRLIEFLNQGLPVSVLDNIHEWTSMSKADILRVTGINERNVARRKSAGRTLTPD
ESERVARFVRVLDAAVDYFGSKEEAWTWLQAPVRGLGNMAPVDLIATETGALEVTDLIGRLEHGVFA

Download         Length: 444 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References