Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 4507777..4508369 Replicon chromosome
Accession NZ_CP109694
Organism Enterobacter asburiae strain 2017-45-54-05

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag OI909_RS21950 Protein ID WP_182072249.1
Coordinates 4508067..4508369 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag OI909_RS21945 Protein ID WP_096151293.1
Coordinates 4507777..4508064 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OI909_RS21940 (OI909_21935) 4506149..4507780 + 1632 WP_033144374.1 Na/Pi cotransporter family protein -
OI909_RS21945 (OI909_21940) 4507777..4508064 - 288 WP_096151293.1 putative addiction module antidote protein Antitoxin
OI909_RS21950 (OI909_21945) 4508067..4508369 - 303 WP_182072249.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OI909_RS21955 (OI909_21950) 4508567..4509439 + 873 WP_033144377.1 23S rRNA pseudouridine(2604) synthase RluF -
OI909_RS21960 (OI909_21955) 4509440..4509712 - 273 WP_023309994.1 DUF3811 domain-containing protein -
OI909_RS21965 (OI909_21960) 4509763..4510707 - 945 WP_096151294.1 ketopantoate/pantoate/pantothenate transporter PanS -
OI909_RS21970 (OI909_21965) 4510801..4512150 - 1350 WP_023309996.1 lysine-sensitive aspartokinase 3 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-92)

Antitoxin

Uncharacterized protein HI1420

(3-90)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11284.02 Da        Isoelectric Point: 9.9325

>T262009 WP_182072249.1 NZ_CP109694:c4508369-4508067 [Enterobacter asburiae]
MKEIVQTESFQRWEQNLKDRRAKTIIASRLFRLANGLAGDIKPVGEGISELRIHYGPGYRLYFKDQGNCIIVLLCGGDKS
SQARDILMAKMLSNPNGRSE

Download         Length: 303 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10183.66 Da        Isoelectric Point: 5.6557

>AT262009 WP_096151293.1 NZ_CP109694:c4508064-4507777 [Enterobacter asburiae]
MHKLTPYDPANALVDDEEIAVFMADALETGDSAYIAKALGVIARAKGMSTISQQTGLSREQLYRSFSDKGNPTLKTTLAV
MKALGLGLTIKHAED

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References