Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3390100..3390757 Replicon chromosome
Accession NZ_CP109694
Organism Enterobacter asburiae strain 2017-45-54-05

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag OI909_RS16555 Protein ID WP_182071664.1
Coordinates 3390100..3390510 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V3PWU7
Locus tag OI909_RS16560 Protein ID WP_010435322.1
Coordinates 3390491..3390757 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OI909_RS16535 (OI909_16530) 3386093..3387826 - 1734 WP_039262981.1 single-stranded-DNA-specific exonuclease RecJ -
OI909_RS16540 (OI909_16535) 3387832..3388545 - 714 WP_047060452.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
OI909_RS16545 (OI909_16540) 3388574..3389470 - 897 WP_023309098.1 site-specific tyrosine recombinase XerD -
OI909_RS16550 (OI909_16545) 3389572..3390093 + 522 WP_039262979.1 flavodoxin FldB -
OI909_RS16555 (OI909_16550) 3390100..3390510 - 411 WP_182071664.1 protein YgfX Toxin
OI909_RS16560 (OI909_16555) 3390491..3390757 - 267 WP_010435322.1 FAD assembly factor SdhE Antitoxin
OI909_RS16565 (OI909_16560) 3391052..3392032 + 981 WP_029739202.1 tRNA-modifying protein YgfZ -
OI909_RS16570 (OI909_16565) 3392107..3392766 - 660 WP_033146591.1 hemolysin III family protein -
OI909_RS16575 (OI909_16570) 3392932..3393243 - 312 WP_048980550.1 N(4)-acetylcytidine aminohydrolase -
OI909_RS16580 (OI909_16575) 3393295..3394026 + 732 WP_032660101.1 MurR/RpiR family transcriptional regulator -
OI909_RS16585 (OI909_16580) 3394143..3395576 + 1434 WP_096151314.1 6-phospho-beta-glucosidase BglA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16111.11 Da        Isoelectric Point: 10.9468

>T262006 WP_182071664.1 NZ_CP109694:c3390510-3390100 [Enterobacter asburiae]
VVLWQSDLRVSWRSQWMSLLLHGLIAAFVLLMPWPLSYTPLWLLLLSFVVFDSVRSQRRINARQGEIKLLMDSRLRWQGK
EWDILGMPWMLNCGMMLRLRKVDGGRCQHLWLAADSMDAAEWRDLRRMLLQQTTQG

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10555.02 Da        Isoelectric Point: 5.1340

>AT262006 WP_010435322.1 NZ_CP109694:c3390757-3390491 [Enterobacter asburiae]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSDDDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB V3PWU7

References