Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3442129..3442786 Replicon chromosome
Accession NZ_CP109692
Organism Enterobacter asburiae strain 2017-45-80

Toxin (Protein)


Gene name cptA Uniprot ID A0A1H8U0Q4
Locus tag OI907_RS16975 Protein ID WP_021242050.1
Coordinates 3442376..3442786 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V3PWU7
Locus tag OI907_RS16970 Protein ID WP_010435322.1
Coordinates 3442129..3442395 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OI907_RS16945 (OI907_16925) 3437310..3438743 - 1434 WP_033146593.1 6-phospho-beta-glucosidase BglA -
OI907_RS16950 (OI907_16930) 3438860..3439591 - 732 WP_029739204.1 MurR/RpiR family transcriptional regulator -
OI907_RS16955 (OI907_16935) 3439643..3439954 + 312 WP_033146592.1 N(4)-acetylcytidine aminohydrolase -
OI907_RS16960 (OI907_16940) 3440120..3440779 + 660 WP_033146591.1 hemolysin III family protein -
OI907_RS16965 (OI907_16945) 3440854..3441834 - 981 WP_033146590.1 tRNA-modifying protein YgfZ -
OI907_RS16970 (OI907_16950) 3442129..3442395 + 267 WP_010435322.1 FAD assembly factor SdhE Antitoxin
OI907_RS16975 (OI907_16955) 3442376..3442786 + 411 WP_021242050.1 protein YgfX Toxin
OI907_RS16980 (OI907_16960) 3442793..3443314 - 522 WP_023309099.1 flavodoxin FldB -
OI907_RS16985 (OI907_16965) 3443416..3444312 + 897 WP_023309098.1 site-specific tyrosine recombinase XerD -
OI907_RS16990 (OI907_16970) 3444341..3445054 + 714 WP_029740340.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
OI907_RS16995 (OI907_16975) 3445060..3446793 + 1734 WP_033146589.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16097.08 Da        Isoelectric Point: 10.9468

>T261986 WP_021242050.1 NZ_CP109692:3442376-3442786 [Enterobacter asburiae]
VVLWQSDLRVSWRSQWMSLLLHGLVAAFVLLMPWPLSYTPLWLLLLSFVVFDSVRSQRRINARQGEIKLLMDSRLRWQGK
EWDILGMPWMLNCGMMLRLRKVDGGRCQHLWLAADSMDAAEWRDLRRMLLQQTTQG

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10555.02 Da        Isoelectric Point: 5.1340

>AT261986 WP_010435322.1 NZ_CP109692:3442129-3442395 [Enterobacter asburiae]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSDDDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1H8U0Q4

Antitoxin

Source ID Structure
AlphaFold DB V3PWU7

References