Detailed information of TA system TA026191

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 3345768..3346380
• Replicon: chromosome
• Accession: NC_017039
• Organism: Synechocystis sp. PCC 6803 substr. PCC-P

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: SYNPCCP_RS15525
• Protein ID: WP_010874170.1
• Coordinates: 3346018..3346380 (+)
• Length: 121 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: SYNPCCP_RS15520
• Protein ID: WP_010874169.1
• Coordinates: 3345768..3346028 (+)
• Length: 87 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SYNPCCP_RS15505	3342854..3343642	-	789	WP_010874166.1	hypothetical protein	-
SYNPCCP_RS15510	3343688..3344644	-	957	WP_010874167.1	quinolinate synthase NadA	-
SYNPCCP_RS15515	3344737..3345483	-	747	WP_010874168.1	cytochrome c biogenesis protein CcdA	-
SYNPCCP_RS15520	3345768..3346028	+	261	WP_010874169.1	hypothetical protein	Antitoxin
SYNPCCP_RS15525	3346018..3346380	+	363	WP_010874170.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
SYNPCCP_RS15530	3346517..3349123	+	2607	WP_010874171.1	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase	-
SYNPCCP_RS15535	3349353..3350180	+	828	WP_010874172.1	hypothetical protein	-
SYNPCCP_RS15540	3350509..3351030	+	522	WP_010874173.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-2 (37-110)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 121 a.a.
• Molecular weight: 13679.59 Da
• Isoelectric Point: 8.2767

>T26191 WP_010874170.1 NC_017039:3346018-3346380 [Synechocystis sp. PCC 6803 substr. PCC-P]
MSNNLHLVNIDFTPEYRRSLKYLAKKYRNIRSDVQPIIEALQKGVISGDRLAGFGSDIYVYKLRIKNSNIQKGKSSGYRL
IYLLESENSILLLTIYSKAEQEDIAASDINSILGEYSIED

Nucleotide

• Length: 363 bp

>T26191 NC_017039:3346018-3346380 [Synechocystis sp. PCC 6803 substr. PCC-P]
ATGTCGAATAATCTCCATTTAGTCAATATCGACTTCACCCCCGAATATAGGAGAAGTTTAAAATATTTAGCCAAGAAATA
TCGAAATATTCGTTCTGATGTTCAGCCCATTATTGAGGCTTTGCAAAAAGGCGTCATTAGTGGTGATCGCCTGGCAGGGT
TTGGCTCTGATATTTACGTCTATAAGCTTAGAATTAAGAATAGTAATATTCAGAAAGGGAAAAGTTCTGGCTACCGATTA
ATTTATTTACTCGAATCAGAAAACAGTATTTTGTTGTTAACCATTTACAGTAAAGCTGAACAAGAAGATATTGCCGCTAG
TGACATTAATTCAATTTTAGGGGAGTACTCCATAGAAGACTAA

Antitoxin

Protein

• Length: 87 a.a.
• Molecular weight: 9909.29 Da
• Isoelectric Point: 4.3705

>AT26191 WP_010874169.1 NC_017039:3345768-3346028 [Synechocystis sp. PCC 6803 substr. PCC-P]
MMRAFEVMATVKDSKQLLLDSDLHWNTSRVKVIILESDELASKGSEFDPDDTPVEEIKVSLRKALEEYKQGKRIPVENMW
EGIDVE

Nucleotide

• Length: 261 bp

>AT26191 NC_017039:3345768-3346028 [Synechocystis sp. PCC 6803 substr. PCC-P]
ATGATGAGAGCTTTTGAGGTAATGGCCACAGTTAAAGATTCCAAACAATTGCTCTTGGATAGTGATTTGCATTGGAATAC
CAGCCGAGTCAAGGTGATTATTTTGGAATCAGATGAATTGGCATCAAAAGGAAGTGAGTTTGATCCTGATGACACGCCTG
TCGAAGAAATTAAGGTGAGTTTGAGGAAGGCATTAGAGGAATATAAACAAGGAAAAAGAATTCCAGTAGAAAATATGTGG
GAGGGAATTGATGTCGAATAA