Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1979067..1979212 Replicon chromosome
Accession NZ_CP109607
Organism Klebsiella pneumoniae strain KP18-231

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1979103..1979205 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1979067..1979212 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OGW23_RS09650 (OGW23_09650) 1974197..1976257 + 2061 WP_004151449.1 oligopeptidase B -
OGW23_RS09655 (OGW23_09655) 1976261..1976920 - 660 WP_021440386.1 exodeoxyribonuclease X -
OGW23_RS09660 (OGW23_09660) 1976999..1977229 - 231 WP_002911406.1 DNA polymerase III subunit theta -
OGW23_RS09665 (OGW23_09665) 1977342..1977716 + 375 WP_004151448.1 CopC domain-containing protein YobA -
OGW23_RS09670 (OGW23_09670) 1977720..1978589 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
OGW23_RS09675 (OGW23_09675) 1978606..1978944 + 339 WP_002911404.1 YebY family protein -
- 1979067..1979212 - 146 - - Antitoxin
- 1979103..1979205 + 103 - - Toxin
OGW23_RS09680 (OGW23_09680) 1979580..1979723 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
OGW23_RS09685 (OGW23_09685) 1979828..1980796 - 969 WP_004151446.1 VirK/YbjX family protein -
OGW23_RS09690 (OGW23_09690) 1980953..1981606 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
OGW23_RS09695 (OGW23_09695) 1981603..1981794 - 192 WP_002911395.1 YebW family protein -
OGW23_RS09700 (OGW23_09700) 1981892..1982131 - 240 WP_002911393.1 YebV family protein -
OGW23_RS09705 (OGW23_09705) 1982247..1983680 - 1434 WP_032415191.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T261908 NZ_CP109607:1979103-1979205 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT261908 NZ_CP109607:c1979212-1979067 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References