Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/-
Location 4216581..4217781 Replicon chromosome
Accession NZ_CP109606
Organism Pseudomonas putida strain QH1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag OGV21_RS19105 Protein ID WP_071984576.1
Coordinates 4217215..4217781 (+) Length 189 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag OGV21_RS19100 Protein ID WP_264316346.1
Coordinates 4216581..4217150 (+) Length 190 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OGV21_RS19085 4212875..4213948 + 1074 WP_060493897.1 microcin C ABC transporter permease YejB -
OGV21_RS19090 4213950..4214969 + 1020 WP_012273316.1 ABC transporter permease -
OGV21_RS19095 4214971..4216578 + 1608 WP_012273317.1 ABC transporter ATP-binding protein -
OGV21_RS19100 4216581..4217150 + 570 WP_264316346.1 helix-turn-helix transcriptional regulator Antitoxin
OGV21_RS19105 4217215..4217781 + 567 WP_071984576.1 HD domain-containing protein Toxin
OGV21_RS19110 4217923..4220853 + 2931 WP_264316347.1 aminotransferase -
OGV21_RS19115 4220857..4222092 - 1236 WP_060493899.1 NAD(P)/FAD-dependent oxidoreductase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(16-166)

Antitoxin

(13-65)


Sequences


Toxin        


Download         Length: 189 a.a.        Molecular weight: 21024.77 Da        Isoelectric Point: 5.5835

>T261901 WP_071984576.1 NZ_CP109606:4217215-4217781 [Pseudomonas putida]
MPNHNLHGKLDFLRQAEKLKNVTRSAHTSTGRRESTAEHSWRLALLALVFEQELGDVDICKVLKLCLVHDLGEALSGDVP
APQAHAVPDKGTNERQDLVAMTSMLEPSMQDSIVGLFDEYEAASTPEAKVVKALDKIETLLQHTQGDNPPGFDYAFNLEY
GRRYTDAIPFLASLRRVIDEETRKRLNS

Download         Length: 567 bp


Antitoxin


Download         Length: 190 a.a.        Molecular weight: 20696.50 Da        Isoelectric Point: 7.1490

>AT261901 WP_264316346.1 NZ_CP109606:4216581-4217150 [Pseudomonas putida]
MNTSPSLRSTPIGPLLKHWRLLNRVKQLHAAQMFGVCQSTISRWESGAQDAEPEQRARIEALLKAKLSSAADHALARLVS
GSSQPVHLVCDLTHRLLACSPSREAEFSVPISDLLGVSLWPFATEEIASQEQRLAGIGWHDNQASPALEFTTGTNDSALV
PIQHSLCRWTRFTLSDGSTARLVETLAHI

Download         Length: 570 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References