Detailed information of TA system TA261901

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/-
• Location: 4216581..4217781
• Replicon: chromosome
• Accession: NZ_CP109606
• Organism: Pseudomonas putida strain QH1

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: OGV21_RS19105
• Protein ID: WP_071984576.1
• Coordinates: 4217215..4217781 (+)
• Length: 189 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: OGV21_RS19100
• Protein ID: WP_264316346.1
• Coordinates: 4216581..4217150 (+)
• Length: 190 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OGV21_RS19085	4212875..4213948	+	1074	WP_060493897.1	microcin C ABC transporter permease YejB	-
OGV21_RS19090	4213950..4214969	+	1020	WP_012273316.1	ABC transporter permease	-
OGV21_RS19095	4214971..4216578	+	1608	WP_012273317.1	ABC transporter ATP-binding protein	-
OGV21_RS19100	4216581..4217150	+	570	WP_264316346.1	helix-turn-helix transcriptional regulator	Antitoxin
OGV21_RS19105	4217215..4217781	+	567	WP_071984576.1	HD domain-containing protein	Toxin
OGV21_RS19110	4217923..4220853	+	2931	WP_264316347.1	aminotransferase	-
OGV21_RS19115	4220857..4222092	-	1236	WP_060493899.1	NAD(P)/FAD-dependent oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• HD domain (16-166)

Antitoxin

• Cro/C1-type helix-turn-helix domain (13-65)

Sequences

Toxin

Protein

• Length: 189 a.a.
• Molecular weight: 21024.77 Da
• Isoelectric Point: 5.5835

>T261901 WP_071984576.1 NZ_CP109606:4217215-4217781 [Pseudomonas putida]
MPNHNLHGKLDFLRQAEKLKNVTRSAHTSTGRRESTAEHSWRLALLALVFEQELGDVDICKVLKLCLVHDLGEALSGDVP
APQAHAVPDKGTNERQDLVAMTSMLEPSMQDSIVGLFDEYEAASTPEAKVVKALDKIETLLQHTQGDNPPGFDYAFNLEY
GRRYTDAIPFLASLRRVIDEETRKRLNS

Nucleotide

• Length: 567 bp

Antitoxin

Protein

• Length: 190 a.a.
• Molecular weight: 20696.50 Da
• Isoelectric Point: 7.1490

>AT261901 WP_264316346.1 NZ_CP109606:4216581-4217150 [Pseudomonas putida]
MNTSPSLRSTPIGPLLKHWRLLNRVKQLHAAQMFGVCQSTISRWESGAQDAEPEQRARIEALLKAKLSSAADHALARLVS
GSSQPVHLVCDLTHRLLACSPSREAEFSVPISDLLGVSLWPFATEEIASQEQRLAGIGWHDNQASPALEFTTGTNDSALV
PIQHSLCRWTRFTLSDGSTARLVETLAHI

Nucleotide

• Length: 570 bp