261900

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 4092477..4093519 Replicon chromosome
Accession NZ_CP109606
Organism Pseudomonas putida strain QH1

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag OGV21_RS18510 Protein ID WP_003153636.1
Coordinates 4092477..4093052 (-) Length 192 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID I3TV68
Locus tag OGV21_RS18515 Protein ID WP_003050245.1
Coordinates 4093049..4093519 (-) Length 157 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OGV21_RS18485 4088915..4089640 - 726 WP_003050273.1 CBASS effector endonuclease NucC -
OGV21_RS18490 4089679..4090581 - 903 WP_003153640.1 CBASS oligonucleotide cyclase -
OGV21_RS18495 4090581..4091081 - 501 WP_003090159.1 type III CBASS phage resistance system CD-NTase-associated protein Cap7 -
OGV21_RS18500 4091078..4091548 - 471 WP_003153638.1 type III CBASS phage resistance system CD-NTase-associated protein Cap8 -
OGV21_RS18505 4091545..4092459 - 915 WP_003050256.1 AAA family ATPase -
OGV21_RS18510 4092477..4093052 - 576 WP_003153636.1 PIN domain-containing protein Toxin
OGV21_RS18515 4093049..4093519 - 471 WP_003050245.1 helix-turn-helix domain-containing protein Antitoxin
OGV21_RS18520 4093723..4094106 + 384 WP_003090167.1 RAQPRD family integrative conjugative element protein -
OGV21_RS18525 4094103..4094336 + 234 WP_003050225.1 TIGR03758 family integrating conjugative element protein -
OGV21_RS18530 4094353..4094712 + 360 WP_003153634.1 TIGR03745 family integrating conjugative element membrane protein -
OGV21_RS18535 4094725..4095135 + 411 WP_003821108.1 TIGR03750 family conjugal transfer protein -
OGV21_RS18540 4095132..4095824 + 693 WP_012614071.1 TIGR03746 family integrating conjugative element protein -
OGV21_RS18545 4095821..4096732 + 912 WP_004350604.1 TIGR03749 family integrating conjugative element protein -
OGV21_RS18550 4096722..4098140 + 1419 WP_004350605.1 TIGR03752 family integrating conjugative element protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(9-114)

Antitoxin

Helix-turn-helix domain, group 17

(85-133)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21629.78 Da        Isoelectric Point: 5.9995

>T261900 WP_003153636.1 NZ_CP109606:c4093052-4092477 [Pseudomonas putida]
MRHSPFTAVYDACVLYPAPLRDFLMWLGLSGRFRARWSQAIHEEWKRNLLINRPDLTRVQVDRTSDLMDRAIPDGLVEGY
EALVAGLTLPDPNDRHVLAAAIRCGASVIVTFNERDFPNDLLAPYGIESQHPDEFVDNLLDLDAAAVVSAAQRQRAQLKH
PPIDVDRYLEILLRQGLVQTTKVLATYRTIL

Download         Length: 576 bp

Antitoxin


Download         Length: 157 a.a.        Molecular weight: 17245.62 Da        Isoelectric Point: 6.3803

>AT261900 WP_003050245.1 NZ_CP109606:c4093519-4093049 [Pseudomonas putida]
MTTATAQSKMTLPAAGEVKAAVQGQRALAAYLATQFETQHIQIFDDHKQAHQVELPTSALRLLVDILAELADGNAVKVVP
VHAELTTQEAADLLNVSRPHFVKLLEDGVLAFHRTGKHRRVRFADLMQYKEARERASEQAMAELAQQSQELGMGYE

Download         Length: 471 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB I3TV68

References