Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /RES-TIGR02293 |
| Location | 2226590..2227473 | Replicon | chromosome |
| Accession | NZ_CP109606 | ||
| Organism | Pseudomonas putida strain QH1 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | B0KLK3 |
| Locus tag | OGV21_RS10145 | Protein ID | WP_012271731.1 |
| Coordinates | 2227036..2227473 (+) | Length | 146 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | B0KLK2 |
| Locus tag | OGV21_RS10140 | Protein ID | WP_012271730.1 |
| Coordinates | 2226590..2227039 (+) | Length | 150 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| OGV21_RS10115 | 2222036..2223235 | + | 1200 | WP_060492790.1 | sugar transporter | - |
| OGV21_RS10120 | 2223286..2223870 | - | 585 | WP_012271726.1 | LysE family transporter | - |
| OGV21_RS10125 | 2223921..2224751 | - | 831 | WP_082421375.1 | AraC family transcriptional regulator | - |
| OGV21_RS10130 | 2224800..2225723 | - | 924 | WP_041166461.1 | LysR family transcriptional regulator | - |
| OGV21_RS10135 | 2225827..2226480 | + | 654 | WP_012271729.1 | oxygen-insensitive NAD(P)H-dependent nitroreductase NfsB | - |
| OGV21_RS10140 | 2226590..2227039 | + | 450 | WP_012271730.1 | DUF2384 domain-containing protein | Antitoxin |
| OGV21_RS10145 | 2227036..2227473 | + | 438 | WP_012271731.1 | RES family NAD+ phosphorylase | Toxin |
| OGV21_RS10150 | 2227481..2228635 | - | 1155 | WP_264316989.1 | aminotransferase class V-fold PLP-dependent enzyme | - |
| OGV21_RS10155 | 2228830..2229756 | - | 927 | WP_012271733.1 | LysR family transcriptional regulator | - |
| OGV21_RS10160 | 2229897..2231126 | + | 1230 | WP_264316990.1 | acyl-CoA dehydrogenase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 146 a.a. Molecular weight: 16000.32 Da Isoelectric Point: 6.2187
>T261899 WP_012271731.1 NZ_CP109606:2227036-2227473 [Pseudomonas putida]
VILWRISAYADLSGTGGLRVSGRWHQAGRPVVYAATSPPGAMLEVLVHLEIDPEDFPTTLRLIRIELPDTVSQARLPTLQ
PGWSAQPELTRALGNRFLDDCSALLLPVPSAIMPSTTNYLFNPRHPQAQSAKIQVEDFTPDSRLF
VILWRISAYADLSGTGGLRVSGRWHQAGRPVVYAATSPPGAMLEVLVHLEIDPEDFPTTLRLIRIELPDTVSQARLPTLQ
PGWSAQPELTRALGNRFLDDCSALLLPVPSAIMPSTTNYLFNPRHPQAQSAKIQVEDFTPDSRLF
Download Length: 438 bp
Antitoxin
Download Length: 150 a.a. Molecular weight: 17034.57 Da Isoelectric Point: 6.1074
>AT261899 WP_012271730.1 NZ_CP109606:2226590-2227039 [Pseudomonas putida]
MLAEVLRDNGYHEYRARLNALLEIPELASDFEIHTRITHGFAATWLVKLTERGVLTPVERDQIIPLRTLKTRIERDQPLT
VDESDRLFRSAHITAMAEAVFGEADKAKRWLSKPKERFSGLTPMQMLTTQQGTTQVEEMLLQIAEGFGL
MLAEVLRDNGYHEYRARLNALLEIPELASDFEIHTRITHGFAATWLVKLTERGVLTPVERDQIIPLRTLKTRIERDQPLT
VDESDRLFRSAHITAMAEAVFGEADKAKRWLSKPKERFSGLTPMQMLTTQQGTTQVEEMLLQIAEGFGL
Download Length: 450 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | B0KLK3 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A7Y3UUY4 |