Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1912435..1912580 Replicon chromosome
Accession NZ_CP109604
Organism Klebsiella pneumoniae strain KP2022

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1912471..1912573 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1912435..1912580 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KP2022_RS09380 1907565..1909625 + 2061 WP_004151449.1 oligopeptidase B -
KP2022_RS09385 1909629..1910288 - 660 WP_002911407.1 exodeoxyribonuclease X -
KP2022_RS09390 1910367..1910597 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KP2022_RS09395 1910710..1911084 + 375 WP_048279882.1 CopC domain-containing protein YobA -
KP2022_RS09400 1911088..1911957 + 870 WP_048279880.1 copper homeostasis membrane protein CopD -
KP2022_RS09405 1911974..1912312 + 339 WP_002911404.1 YebY family protein -
- 1912435..1912580 - 146 - - Antitoxin
- 1912471..1912573 + 103 - - Toxin
KP2022_RS09410 1912948..1913091 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KP2022_RS09415 1913196..1914164 - 969 WP_004151446.1 VirK/YbjX family protein -
KP2022_RS09420 1914321..1914974 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
KP2022_RS09425 1914971..1915162 - 192 WP_002911395.1 YebW family protein -
KP2022_RS09430 1915260..1915499 - 240 WP_002911393.1 YebV family protein -
KP2022_RS09435 1915615..1917048 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T261887 NZ_CP109604:1912471-1912573 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT261887 NZ_CP109604:c1912580-1912435 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References