Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 5466086..5467125 Replicon chromosome
Accession NZ_CP109603
Organism Pseudomonas putida strain SEH01

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag OGV19_RS24645 Protein ID WP_264311048.1
Coordinates 5466086..5466661 (-) Length 192 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag OGV19_RS24650 Protein ID WP_264311049.1
Coordinates 5466661..5467125 (-) Length 155 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OGV19_RS24630 5461617..5462246 + 630 WP_264311045.1 isochorismate family cysteine hydrolase YcaC -
OGV19_RS24635 5462477..5464264 - 1788 WP_264311046.1 monovalent cation:proton antiporter-2 (CPA2) family protein -
OGV19_RS24640 5464447..5465934 - 1488 WP_264311047.1 YifB family Mg chelatase-like AAA ATPase -
OGV19_RS24645 5466086..5466661 - 576 WP_264311048.1 PIN domain-containing protein Toxin
OGV19_RS24650 5466661..5467125 - 465 WP_264311049.1 helix-turn-helix domain-containing protein Antitoxin
OGV19_RS24655 5467499..5469511 + 2013 WP_264311050.1 DUF4034 domain-containing protein -
OGV19_RS24660 5469537..5469965 - 429 WP_264311051.1 TOBE domain-containing protein -
OGV19_RS24665 5469989..5470252 - 264 WP_264311052.1 accessory factor UbiK family protein -
OGV19_RS24670 5470631..5470969 + 339 WP_002555808.1 P-II family nitrogen regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - algC 5416024..5482999 66975


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(8-115)

Antitoxin

SinI-like, DNA-binding domain

(84-130)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21777.24 Da        Isoelectric Point: 5.2939

>T261883 WP_264311048.1 NZ_CP109603:c5466661-5466086 [Pseudomonas putida]
MRQSPFTVVYDACVLYPAPLRDLLMHLALTGVYRARWSEQIHDEWTRNVLKNRPDIAAAQLARTVAFMNQAVADSLVSDY
EPLIQGLDLPDEDDRHVLAAAIKCGATVIVTYNLKDFPPTILKRFEIEALHPDVFLSDIWDLDQAAVLEAVKKQRVALKN
PVYTPRELLDTLLKQRLPEIVKQLSNYELLI

Download         Length: 576 bp

Antitoxin


Download         Length: 155 a.a.        Molecular weight: 16905.40 Da        Isoelectric Point: 5.2440

>AT261883 WP_264311049.1 NZ_CP109603:c5467125-5466661 [Pseudomonas putida]
MTTADLAQTILPDEKAIAAAIESSRQIAAFLSTKLDTQRIELVDEAQQRQTVELPTFALRLLGDILNELALGNTVKVVPI
HAELTTQEGADMLNVSRPHLVKLLDEGLIPHTKTGSHRRIKFTDLMAYKAERDKASQAAMEALAAQAQELNMGY

Download         Length: 465 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References