Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 4944927..4945532 Replicon chromosome
Accession NZ_CP109603
Organism Pseudomonas putida strain SEH01

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag OGV19_RS22315 Protein ID WP_264310671.1
Coordinates 4945242..4945532 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OGV19_RS22310 Protein ID WP_264310670.1
Coordinates 4944927..4945232 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OGV19_RS22290 4941060..4943309 + 2250 WP_264310667.1 AsmA family protein -
OGV19_RS22295 4943306..4944373 + 1068 WP_264310668.1 A/G-specific adenine glycosylase -
OGV19_RS22300 4944370..4944642 + 273 WP_264310669.1 oxidative damage protection protein -
OGV19_RS22310 4944927..4945232 - 306 WP_264310670.1 putative addiction module antidote protein Antitoxin
OGV19_RS22315 4945242..4945532 - 291 WP_264310671.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OGV19_RS22320 4945709..4946671 + 963 WP_264310672.1 polyphosphate kinase 2 -
OGV19_RS22325 4946681..4947214 - 534 WP_264310673.1 hypothetical protein -
OGV19_RS22330 4947344..4947787 + 444 WP_027594262.1 hypothetical protein -
OGV19_RS22335 4947960..4949345 - 1386 WP_264310674.1 GABA permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 4938226..4979298 41072


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-96)

Antitoxin

Cro/C1-type helix-turn-helix domain

(46-90)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10737.51 Da        Isoelectric Point: 10.3650

>T261882 WP_264310671.1 NZ_CP109603:c4945532-4945242 [Pseudomonas putida]
MHILIQTETYKGWFAALRDARAQARINVRLRRIELGMLGDCKPVGEGVSEARINYGPGHRVYFVQRGYEVIILLAGGDKA
SQARDIKAALKLARDL

Download         Length: 291 bp

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10786.46 Da        Isoelectric Point: 4.7914

>AT261882 WP_264310670.1 NZ_CP109603:c4945232-4944927 [Pseudomonas putida]
MTDIKLTKWDAVDHLKTEQDIALYLEACLEENDPALLAAALGDVARARGMAQLARDTGLTREGLYKALSAEGNPSLATIM
KVMAALGVRLHAEVVQPQVAG

Download         Length: 306 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References