261880

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 4241633..4242317 Replicon chromosome
Accession NZ_CP109603
Organism Pseudomonas putida strain SEH01

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag OGV19_RS18995 Protein ID WP_264310160.1
Coordinates 4241633..4242004 (+) Length 124 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag OGV19_RS19000 Protein ID WP_264310161.1
Coordinates 4241997..4242317 (+) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OGV19_RS18965 4237130..4237855 + 726 WP_033701098.1 LPS export ABC transporter ATP-binding protein -
OGV19_RS18970 4238030..4239523 + 1494 WP_264310155.1 RNA polymerase factor sigma-54 -
OGV19_RS18975 4239603..4239911 + 309 WP_264310156.1 ribosome-associated translation inhibitor RaiA -
OGV19_RS18980 4239924..4240388 + 465 WP_264310157.1 PTS IIA-like nitrogen regulatory protein PtsN -
OGV19_RS18985 4240391..4241245 + 855 WP_264310158.1 RNase adapter RapZ -
OGV19_RS18990 4241266..4241538 + 273 WP_264310159.1 HPr family phosphocarrier protein -
OGV19_RS18995 4241633..4242004 + 372 WP_264310160.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OGV19_RS19000 4241997..4242317 + 321 WP_264310161.1 helix-turn-helix transcriptional regulator Antitoxin
OGV19_RS19005 4242344..4243237 - 894 WP_264310162.1 ZIP family metal transporter -
OGV19_RS19010 4243249..4243860 - 612 WP_264310163.1 superoxide dismutase -
OGV19_RS19015 4243862..4244323 - 462 WP_264310164.1 DUF2753 domain-containing protein -
OGV19_RS19020 4244352..4245728 - 1377 WP_264310165.1 class II fumarate hydratase -
OGV19_RS19025 4245721..4246122 - 402 WP_264310166.1 FagA protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(18-111)

Antitoxin

HigA2-like, helix-turn-helix domain

(11-90)


Sequences

Toxin        


Download         Length: 124 a.a.        Molecular weight: 13524.49 Da        Isoelectric Point: 9.8659

>T261880 WP_264310160.1 NZ_CP109603:4241633-4242004 [Pseudomonas putida]
MDAYKGVKPLYWVGSSKKDLQGAPRDVQDVFGFALYLAQEGGKHYQAKSLRGFAGAGVLEVVENHDSDTYRAIYTVNLGG
AVYVLHCFQKKSSTGIKTPKHEVDLIKSRLKLAMAHAKGTKHD

Download         Length: 372 bp

>T261880 NZ_CP109603:4241633-4242004 [Pseudomonas putida]
ATGGATGCATACAAAGGTGTCAAACCGCTGTACTGGGTAGGGAGCAGCAAGAAGGATCTGCAGGGTGCTCCAAGGGATGT
GCAAGATGTATTTGGCTTTGCCTTGTATCTGGCACAGGAAGGCGGAAAGCATTATCAAGCGAAAAGCCTGAGGGGCTTTG
CCGGTGCAGGGGTATTGGAGGTAGTTGAAAACCACGATAGTGATACCTATCGCGCCATCTACACCGTGAACCTGGGCGGC
GCAGTCTACGTACTGCATTGTTTCCAGAAAAAATCCAGCACGGGCATCAAAACCCCCAAACATGAAGTGGACTTGATCAA
ATCGAGACTCAAGCTCGCAATGGCTCACGCAAAAGGAACAAAACATGATTGA

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 11675.74 Da        Isoelectric Point: 9.8520

>AT261880 WP_264310161.1 NZ_CP109603:4241997-4242317 [Pseudomonas putida]
MIEIEEGSTNVYADLNSPDASEMLIKAHLASKICSIIKARHLTQVQAAAVLGLPQPKVSEMMRGKFRGISETKMIDCLAR
LGRDIQIVVKAAPRSRREGRVEVIFA

Download         Length: 321 bp

>AT261880 NZ_CP109603:4241997-4242317 [Pseudomonas putida]
ATGATTGAGATCGAAGAAGGCAGCACAAACGTCTATGCCGACCTCAACAGCCCAGACGCCAGCGAGATGCTGATCAAGGC
TCACCTGGCCAGCAAGATCTGCAGCATCATCAAGGCACGCCACCTGACTCAAGTCCAGGCCGCGGCGGTACTCGGGCTCC
CCCAACCCAAAGTCTCCGAAATGATGCGAGGGAAGTTTCGCGGCATCAGCGAAACCAAAATGATTGATTGCCTGGCACGC
CTTGGCCGCGATATTCAGATTGTAGTGAAGGCAGCACCTCGTTCCCGGCGCGAAGGCCGCGTAGAAGTCATCTTTGCCTG
A

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References