Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 2083653..2084038 Replicon chromosome
Accession NC_017039
Organism Synechocystis sp. PCC 6803 substr. PCC-P

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag SYNPCCP_RS16915 Protein ID WP_080504056.1
Coordinates 2083934..2084038 (+) Length 35 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag SYNPCCP_RS09900 Protein ID WP_010873096.1
Coordinates 2083653..2083937 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SYNPCCP_RS09865 2078712..2080547 + 1836 WP_010873091.1 hypothetical protein -
SYNPCCP_RS09870 2080691..2081743 - 1053 WP_010873092.1 2OG-Fe(II) oxygenase -
SYNPCCP_RS09875 2081970..2082197 + 228 WP_020862282.1 DUF2281 domain-containing protein -
SYNPCCP_RS16910 2082243..2082587 + 345 WP_071822655.1 type II toxin-antitoxin system VapC family toxin -
SYNPCCP_RS09885 2082749..2083033 + 285 WP_014407120.1 BrnT family toxin -
SYNPCCP_RS09890 2083038..2083244 + 207 WP_010873094.1 hypothetical protein -
SYNPCCP_RS09895 2083272..2083511 + 240 WP_010873095.1 hypothetical protein -
SYNPCCP_RS09900 2083653..2083937 + 285 WP_010873096.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
SYNPCCP_RS16915 2083934..2084038 + 105 WP_080504056.1 type II toxin-antitoxin system YoeB family toxin Toxin
SYNPCCP_RS09905 2084132..2084956 - 825 WP_010873097.1 photosystem II manganese-stabilizing polypeptide -
SYNPCCP_RS09910 2085183..2085560 + 378 WP_010873098.1 hypothetical protein -
SYNPCCP_RS09920 2085957..2086319 - 363 WP_010873099.1 hypothetical protein -
SYNPCCP_RS09925 2086507..2087850 + 1344 WP_010873100.1 3-phosphoshikimate 1-carboxyvinyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-32)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(19-83)


Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 4196.90 Da        Isoelectric Point: 8.5633

>T26188 WP_080504056.1 NC_017039:2083934-2084038 [Synechocystis sp. PCC 6803 substr. PCC-P]
VKLIFSEQAWSDYLYWQQNDKKILKRINTLVELI

Download         Length: 105 bp

>T26188 NC_017039:2083934-2084038 [Synechocystis sp. PCC 6803 substr. PCC-P]
GTGAAGCTAATTTTCTCTGAGCAAGCCTGGAGCGATTATCTTTACTGGCAACAAAACGACAAGAAAATACTTAAAAGAAT
CAATACCTTAGTTGAATTAATTTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10540.02 Da        Isoelectric Point: 4.1364

>AT26188 WP_010873096.1 NC_017039:2083653-2083937 [Synechocystis sp. PCC 6803 substr. PCC-P]
MGETLPQQLPNMNAVSQIIAQQKLAAIMEQVCSDHVPTIITRDTQPSVVMISLEDYQSLEETAYLLRSPNNAQKLMSAIK
QLENDQGVERELLE

Download         Length: 285 bp

>AT26188 NC_017039:2083653-2083937 [Synechocystis sp. PCC 6803 substr. PCC-P]
ATGGGGGAAACTTTGCCCCAACAATTGCCAAACATGAACGCAGTCAGCCAAATTATTGCACAACAAAAACTTGCAGCTAT
CATGGAGCAAGTATGTAGTGATCATGTTCCAACAATTATCACCAGGGATACCCAACCATCTGTCGTCATGATTTCCCTGG
AAGACTATCAGTCATTAGAAGAAACAGCATATCTACTACGTAGCCCGAACAATGCTCAAAAATTGATGTCGGCGATCAAG
CAATTAGAAAATGATCAAGGTGTCGAAAGGGAACTATTGGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References