Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-DUF971
Location 702244..702832 Replicon chromosome
Accession NZ_CP109603
Organism Pseudomonas putida strain SEH01

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag OGV19_RS03140 Protein ID WP_264312093.1
Coordinates 702530..702832 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag OGV19_RS03135 Protein ID WP_027593133.1
Coordinates 702244..702537 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OGV19_RS03115 697994..698929 + 936 WP_264312089.1 AEC family transporter -
OGV19_RS03120 699050..700336 - 1287 WP_264312090.1 mechanosensitive ion channel family protein -
OGV19_RS03125 700441..701802 + 1362 WP_264312091.1 DEAD/DEAH box helicase -
OGV19_RS03130 701859..702131 - 273 WP_264312092.1 hypothetical protein -
OGV19_RS03135 702244..702537 - 294 WP_027593133.1 putative addiction module antidote protein Antitoxin
OGV19_RS03140 702530..702832 - 303 WP_264312093.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OGV19_RS03145 702963..703358 + 396 WP_264312094.1 transcriptional regulator -
OGV19_RS03150 703465..704391 + 927 WP_264312095.1 DMT family transporter -
OGV19_RS03155 704401..705582 - 1182 WP_264312096.1 MFS transporter -
OGV19_RS03160 705689..706582 + 894 WP_264312097.1 LysR family transcriptional regulator -
OGV19_RS03165 706707..706835 + 129 WP_256214945.1 PA1414 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(6-93)

Antitoxin

Uncharacterized protein HI1420

(8-93)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11428.13 Da        Isoelectric Point: 10.5383

>T261877 WP_264312093.1 NZ_CP109603:c702832-702530 [Pseudomonas putida]
MKKIESSSFRHWVHGLRDEMARIRIIARINRLMEGLPGDVSAVGHGVSELRVHHGPGYRVYFHQAGDTLVILLCGGDKSS
QRRDIKAAHEILRSWRMQND

Download         Length: 303 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10517.96 Da        Isoelectric Point: 5.5740

>AT261877 WP_027593133.1 NZ_CP109603:c702537-702244 [Pseudomonas putida]
MTETFFEFDAADYLTTPQAIAQFMSDALETGDASYVAKAVGVVARAKGMSDLAKETGLSREQLYRSFSEHGNPTLKSFLA
VMKALGIDMTAKPHLAH

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References