Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 1466446..1467099 Replicon chromosome
Accession NZ_CP107728
Organism Acinetobacter baumannii strain AB44

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag OGT51_RS07085 Protein ID WP_000607077.1
Coordinates 1466710..1467099 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag OGT51_RS07080 Protein ID WP_001288210.1
Coordinates 1466446..1466703 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OGT51_RS07060 (OGT51_07060) 1461962..1462969 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
OGT51_RS07065 (OGT51_07065) 1462988..1463365 + 378 WP_001216380.1 50S ribosomal protein L17 -
OGT51_RS07070 (OGT51_07070) 1463547..1465037 + 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
OGT51_RS07075 (OGT51_07075) 1465086..1466258 - 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
OGT51_RS07080 (OGT51_07080) 1466446..1466703 + 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
OGT51_RS07085 (OGT51_07085) 1466710..1467099 + 390 WP_000607077.1 membrane protein Toxin
OGT51_RS07090 (OGT51_07090) 1467869..1468954 + 1086 WP_000049106.1 hypothetical protein -
OGT51_RS07095 (OGT51_07095) 1469032..1469598 + 567 WP_000651538.1 rhombosortase -
OGT51_RS07100 (OGT51_07100) 1469786..1471981 + 2196 WP_001158906.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T261845 WP_000607077.1 NZ_CP107728:1466710-1467099 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT261845 WP_001288210.1 NZ_CP107728:1466446-1466703 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References