Detailed information of TA system TA026183

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 3345658..3346270
• Replicon: chromosome
• Accession: NC_017038
• Organism: Synechocystis sp. PCC 6803 substr. GT-I

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: SYNGTI_RS15480
• Protein ID: WP_010874170.1
• Coordinates: 3345908..3346270 (+)
• Length: 121 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: SYNGTI_RS15475
• Protein ID: WP_010874169.1
• Coordinates: 3345658..3345918 (+)
• Length: 87 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SYNGTI_RS15460	3342744..3343532	-	789	WP_010874166.1	hypothetical protein	-
SYNGTI_RS15465	3343578..3344534	-	957	WP_010874167.1	quinolinate synthase NadA	-
SYNGTI_RS15470	3344627..3345373	-	747	WP_010874168.1	cytochrome c biogenesis protein CcdA	-
SYNGTI_RS15475	3345658..3345918	+	261	WP_010874169.1	hypothetical protein	Antitoxin
SYNGTI_RS15480	3345908..3346270	+	363	WP_010874170.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
SYNGTI_RS15485	3346407..3349013	+	2607	WP_010874171.1	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase	-
SYNGTI_RS15490	3349243..3350070	+	828	WP_010874172.1	hypothetical protein	-
SYNGTI_RS15495	3350399..3350920	+	522	WP_010874173.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-2 (37-110)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 121 a.a.
• Molecular weight: 13679.59 Da
• Isoelectric Point: 8.2767

>T26183 WP_010874170.1 NC_017038:3345908-3346270 [Synechocystis sp. PCC 6803 substr. GT-I]
MSNNLHLVNIDFTPEYRRSLKYLAKKYRNIRSDVQPIIEALQKGVISGDRLAGFGSDIYVYKLRIKNSNIQKGKSSGYRL
IYLLESENSILLLTIYSKAEQEDIAASDINSILGEYSIED

Nucleotide

• Length: 363 bp

>T26183 NC_017038:3345908-3346270 [Synechocystis sp. PCC 6803 substr. GT-I]
ATGTCGAATAATCTCCATTTAGTCAATATCGACTTCACCCCCGAATATAGGAGAAGTTTAAAATATTTAGCCAAGAAATA
TCGAAATATTCGTTCTGATGTTCAGCCCATTATTGAGGCTTTGCAAAAAGGCGTCATTAGTGGTGATCGCCTGGCAGGGT
TTGGCTCTGATATTTACGTCTATAAGCTTAGAATTAAGAATAGTAATATTCAGAAAGGGAAAAGTTCTGGCTACCGATTA
ATTTATTTACTCGAATCAGAAAACAGTATTTTGTTGTTAACCATTTACAGTAAAGCTGAACAAGAAGATATTGCCGCTAG
TGACATTAATTCAATTTTAGGGGAGTACTCCATAGAAGACTAA

Antitoxin

Protein

• Length: 87 a.a.
• Molecular weight: 9909.29 Da
• Isoelectric Point: 4.3705

>AT26183 WP_010874169.1 NC_017038:3345658-3345918 [Synechocystis sp. PCC 6803 substr. GT-I]
MMRAFEVMATVKDSKQLLLDSDLHWNTSRVKVIILESDELASKGSEFDPDDTPVEEIKVSLRKALEEYKQGKRIPVENMW
EGIDVE

Nucleotide

• Length: 261 bp

>AT26183 NC_017038:3345658-3345918 [Synechocystis sp. PCC 6803 substr. GT-I]
ATGATGAGAGCTTTTGAGGTAATGGCCACAGTTAAAGATTCCAAACAATTGCTCTTGGATAGTGATTTGCATTGGAATAC
CAGCCGAGTCAAGGTGATTATTTTGGAATCAGATGAATTGGCATCAAAAGGAAGTGAGTTTGATCCTGATGACACGCCTG
TCGAAGAAATTAAGGTGAGTTTGAGGAAGGCATTAGAGGAATATAAACAAGGAAAAAGAATTCCAGTAGAAAATATGTGG
GAGGGAATTGATGTCGAATAA