261807

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) BrnTA/BrnT-BrnA
Location 1481..2069 Replicon plasmid unnamed1
Accession NZ_CP107615
Organism Acinetobacter baumannii strain 1326927-2

Toxin (Protein)


Gene name brnT Uniprot ID A0A0J8TIH5
Locus tag OIO47_RS18795 Protein ID WP_000438827.1
Coordinates 1782..2069 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name brnA Uniprot ID N9M5I3
Locus tag OIO47_RS18790 Protein ID WP_001983304.1
Coordinates 1481..1795 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OIO47_RS18790 (OIO47_18790) 1481..1795 - 315 WP_001983304.1 BrnA antitoxin family protein Antitoxin
OIO47_RS18795 (OIO47_18795) 1782..2069 - 288 WP_000438827.1 BrnT family toxin Toxin
OIO47_RS18800 (OIO47_18800) 2316..2618 - 303 WP_000702763.1 hypothetical protein -
OIO47_RS18805 (OIO47_18805) 2712..2996 + 285 WP_001071102.1 hypothetical protein -
OIO47_RS18810 (OIO47_18810) 3011..3505 - 495 WP_000999995.1 hypothetical protein -
OIO47_RS18815 (OIO47_18815) 3541..3717 - 177 WP_000246872.1 hypothetical protein -
OIO47_RS18820 (OIO47_18820) 3999..4211 - 213 WP_000687427.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..19667 19667


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(7-88)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(41-96)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11329.75 Da        Isoelectric Point: 5.6762

>T261807 WP_000438827.1 NZ_CP107615:c2069-1782 [Acinetobacter baumannii]
MEQYFEWDEAKNRKNQKKHDISFETASLVFEDPLRISIQDRYTNGEERWQTIGRVKGVLMLLVAHTIFDEDDCEIIRIIS
ARQVTKAERNKYEHG

Download         Length: 288 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 12208.84 Da        Isoelectric Point: 7.2026

>AT261807 WP_001983304.1 NZ_CP107615:c1795-1481 [Acinetobacter baumannii]
MSMVRYSHKELNEKFGEKQDAEIQRLLAKGTVPDDQLDLSDIPEITDWSNAVRQNQFYRPVKQQTSIRLDADVLAWFKAQ
GKGYQTRMNEILRDAMLKELKNHQ

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0J8TIH5

Antitoxin

Source ID Structure
AlphaFold DB N9M5I3

References