Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 460284..460937 Replicon chromosome
Accession NZ_CP107614
Organism Acinetobacter baumannii strain 1326927-2

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag OIO47_RS02235 Protein ID WP_025467596.1
Coordinates 460548..460937 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag OIO47_RS02230 Protein ID WP_001288210.1
Coordinates 460284..460541 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OIO47_RS02210 (OIO47_02210) 455800..456807 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
OIO47_RS02215 (OIO47_02215) 456826..457203 + 378 WP_001216380.1 50S ribosomal protein L17 -
OIO47_RS02220 (OIO47_02220) 457385..458875 + 1491 WP_000415133.1 NAD(P)/FAD-dependent oxidoreductase -
OIO47_RS02225 (OIO47_02225) 458924..460096 - 1173 WP_031961342.1 acyl-CoA dehydrogenase family protein -
OIO47_RS02230 (OIO47_02230) 460284..460541 + 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
OIO47_RS02235 (OIO47_02235) 460548..460937 + 390 WP_025467596.1 membrane protein Toxin
OIO47_RS02240 (OIO47_02240) 461707..462792 + 1086 WP_000049106.1 hypothetical protein -
OIO47_RS02245 (OIO47_02245) 462870..463436 + 567 WP_000651536.1 rhombosortase -
OIO47_RS02250 (OIO47_02250) 463624..465819 + 2196 WP_001158905.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15609.84 Da        Isoelectric Point: 10.3816

>T261806 WP_025467596.1 NZ_CP107614:460548-460937 [Acinetobacter baumannii]
MINHLNFQLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLH

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT261806 WP_001288210.1 NZ_CP107614:460284-460541 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References