Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 475464..476117 Replicon chromosome
Accession NZ_CP107605
Organism Acinetobacter baumannii strain 1326924-1

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag OIO60_RS02330 Protein ID WP_000607077.1
Coordinates 475728..476117 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag OIO60_RS02325 Protein ID WP_001288210.1
Coordinates 475464..475721 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OIO60_RS02305 (OIO60_02305) 470980..471987 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
OIO60_RS02310 (OIO60_02310) 472006..472383 + 378 WP_001216380.1 50S ribosomal protein L17 -
OIO60_RS02315 (OIO60_02315) 472565..474055 + 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
OIO60_RS02320 (OIO60_02320) 474104..475276 - 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
OIO60_RS02325 (OIO60_02325) 475464..475721 + 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
OIO60_RS02330 (OIO60_02330) 475728..476117 + 390 WP_000607077.1 membrane protein Toxin
OIO60_RS02335 (OIO60_02335) 476887..477972 + 1086 WP_000049106.1 hypothetical protein -
OIO60_RS02340 (OIO60_02340) 478050..478616 + 567 WP_000651538.1 rhombosortase -
OIO60_RS02345 (OIO60_02345) 478804..480999 + 2196 WP_001158906.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T261795 WP_000607077.1 NZ_CP107605:475728-476117 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT261795 WP_001288210.1 NZ_CP107605:475464-475721 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References