Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 460273..460926 Replicon chromosome
Accession NZ_CP107601
Organism Acinetobacter baumannii strain 1326589

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag OIO85_RS02240 Protein ID WP_025467596.1
Coordinates 460537..460926 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag OIO85_RS02235 Protein ID WP_001288210.1
Coordinates 460273..460530 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OIO85_RS02215 (OIO85_02215) 455789..456796 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
OIO85_RS02220 (OIO85_02220) 456815..457192 + 378 WP_001216380.1 50S ribosomal protein L17 -
OIO85_RS02225 (OIO85_02225) 457374..458864 + 1491 WP_000415133.1 NAD(P)/FAD-dependent oxidoreductase -
OIO85_RS02230 (OIO85_02230) 458913..460085 - 1173 WP_031961342.1 acyl-CoA dehydrogenase family protein -
OIO85_RS02235 (OIO85_02235) 460273..460530 + 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
OIO85_RS02240 (OIO85_02240) 460537..460926 + 390 WP_025467596.1 membrane protein Toxin
OIO85_RS02245 (OIO85_02245) 461696..462781 + 1086 WP_000049106.1 hypothetical protein -
OIO85_RS02250 (OIO85_02250) 462859..463425 + 567 WP_000651536.1 rhombosortase -
OIO85_RS02255 (OIO85_02255) 463613..465808 + 2196 WP_001158905.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15609.84 Da        Isoelectric Point: 10.3816

>T261790 WP_025467596.1 NZ_CP107601:460537-460926 [Acinetobacter baumannii]
MINHLNFQLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLH

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT261790 WP_001288210.1 NZ_CP107601:460273-460530 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References