Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 464669..465322 Replicon chromosome
Accession NZ_CP107599
Organism Acinetobacter baumannii strain 1326584

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag OIO43_RS02285 Protein ID WP_000607096.1
Coordinates 464933..465322 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag OIO43_RS02280 Protein ID WP_001288210.1
Coordinates 464669..464926 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OIO43_RS02260 (OIO43_02260) 460185..461192 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
OIO43_RS02265 (OIO43_02265) 461211..461588 + 378 WP_001216380.1 50S ribosomal protein L17 -
OIO43_RS02270 (OIO43_02270) 461770..463260 + 1491 WP_000415137.1 NAD(P)/FAD-dependent oxidoreductase -
OIO43_RS02275 (OIO43_02275) 463309..464481 - 1173 WP_001190543.1 acyl-CoA dehydrogenase family protein -
OIO43_RS02280 (OIO43_02280) 464669..464926 + 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
OIO43_RS02285 (OIO43_02285) 464933..465322 + 390 WP_000607096.1 hypothetical protein Toxin
OIO43_RS02290 (OIO43_02290) 466092..467177 + 1086 WP_000049106.1 hypothetical protein -
OIO43_RS02295 (OIO43_02295) 467255..467821 + 567 WP_000651536.1 rhombosortase -
OIO43_RS02300 (OIO43_02300) 468009..470204 + 2196 WP_001158905.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15583.80 Da        Isoelectric Point: 10.4637

>T261787 WP_000607096.1 NZ_CP107599:464933-465322 [Acinetobacter baumannii]
MINHSNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLH

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT261787 WP_001288210.1 NZ_CP107599:464669-464926 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References