Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 464650..465303 Replicon chromosome
Accession NZ_CP107593
Organism Acinetobacter baumannii strain 1326580

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag OIO74_RS02285 Protein ID WP_000607096.1
Coordinates 464914..465303 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag OIO74_RS02280 Protein ID WP_001288210.1
Coordinates 464650..464907 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OIO74_RS02260 (OIO74_02260) 460166..461173 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
OIO74_RS02265 (OIO74_02265) 461192..461569 + 378 WP_001216380.1 50S ribosomal protein L17 -
OIO74_RS02270 (OIO74_02270) 461751..463241 + 1491 WP_000415137.1 NAD(P)/FAD-dependent oxidoreductase -
OIO74_RS02275 (OIO74_02275) 463290..464462 - 1173 WP_001190543.1 acyl-CoA dehydrogenase family protein -
OIO74_RS02280 (OIO74_02280) 464650..464907 + 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
OIO74_RS02285 (OIO74_02285) 464914..465303 + 390 WP_000607096.1 hypothetical protein Toxin
OIO74_RS02290 (OIO74_02290) 466073..467158 + 1086 WP_000049106.1 hypothetical protein -
OIO74_RS02295 (OIO74_02295) 467236..467802 + 567 WP_000651536.1 rhombosortase -
OIO74_RS02300 (OIO74_02300) 467990..470185 + 2196 WP_001158905.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15583.80 Da        Isoelectric Point: 10.4637

>T261779 WP_000607096.1 NZ_CP107593:464914-465303 [Acinetobacter baumannii]
MINHSNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLH

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT261779 WP_001288210.1 NZ_CP107593:464650-464907 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References