Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3499353..3500006 Replicon chromosome
Accession NZ_CP107590
Organism Acinetobacter baumannii strain 1326569

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag OIO44_RS16875 Protein ID WP_000607077.1
Coordinates 3499353..3499742 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag OIO44_RS16880 Protein ID WP_001288210.1
Coordinates 3499749..3500006 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OIO44_RS16860 (OIO44_16865) 3494471..3496666 - 2196 WP_001158906.1 TRAP transporter large permease subunit -
OIO44_RS16865 (OIO44_16870) 3496854..3497420 - 567 WP_000651538.1 rhombosortase -
OIO44_RS16870 (OIO44_16875) 3497498..3498583 - 1086 WP_000049106.1 hypothetical protein -
OIO44_RS16875 (OIO44_16880) 3499353..3499742 - 390 WP_000607077.1 membrane protein Toxin
OIO44_RS16880 (OIO44_16885) 3499749..3500006 - 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
OIO44_RS16885 (OIO44_16890) 3500194..3501366 + 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
OIO44_RS16890 (OIO44_16895) 3501415..3502905 - 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
OIO44_RS16895 (OIO44_16900) 3503087..3503464 - 378 WP_001216380.1 50S ribosomal protein L17 -
OIO44_RS16900 (OIO44_16905) 3503483..3504490 - 1008 WP_264252364.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T261776 WP_000607077.1 NZ_CP107590:c3499742-3499353 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT261776 WP_001288210.1 NZ_CP107590:c3500006-3499749 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References