Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3493809..3494462 Replicon chromosome
Accession NZ_CP107587
Organism Acinetobacter baumannii strain 1326527-2

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag OIO39_RS16845 Protein ID WP_000607077.1
Coordinates 3493809..3494198 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag OIO39_RS16850 Protein ID WP_001288210.1
Coordinates 3494205..3494462 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OIO39_RS16830 (OIO39_16825) 3488927..3491122 - 2196 WP_001158906.1 TRAP transporter large permease subunit -
OIO39_RS16835 (OIO39_16830) 3491310..3491876 - 567 WP_000651538.1 rhombosortase -
OIO39_RS16840 (OIO39_16835) 3491954..3493039 - 1086 WP_000049106.1 hypothetical protein -
OIO39_RS16845 (OIO39_16840) 3493809..3494198 - 390 WP_000607077.1 membrane protein Toxin
OIO39_RS16850 (OIO39_16845) 3494205..3494462 - 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
OIO39_RS16855 (OIO39_16850) 3494650..3495822 + 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
OIO39_RS16860 (OIO39_16855) 3495871..3497361 - 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
OIO39_RS16865 (OIO39_16860) 3497543..3497920 - 378 WP_001216380.1 50S ribosomal protein L17 -
OIO39_RS16870 (OIO39_16865) 3497939..3498946 - 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T261772 WP_000607077.1 NZ_CP107587:c3494198-3493809 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT261772 WP_001288210.1 NZ_CP107587:c3494462-3494205 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References