Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/DUF433(antitoxin)
Location 545131..545690 Replicon chromosome
Accession NC_017038
Organism Synechocystis sp. PCC 6803 substr. GT-I

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag SYNGTI_RS02505 Protein ID WP_010871694.1
Coordinates 545352..545690 (+) Length 113 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag SYNGTI_RS02500 Protein ID WP_010871693.1
Coordinates 545131..545355 (+) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SYNGTI_RS02475 540164..540865 + 702 WP_071822669.1 HAD family hydrolase -
SYNGTI_RS02480 540965..542167 + 1203 WP_010871689.1 class I SAM-dependent methyltransferase -
SYNGTI_RS02485 542207..542698 - 492 WP_010871690.1 hypothetical protein -
SYNGTI_RS02490 542905..543444 + 540 WP_010871691.1 tellurium resistance TerZ family protein -
SYNGTI_RS02495 543570..544973 - 1404 WP_010871692.1 glutamate decarboxylase -
SYNGTI_RS02500 545131..545355 + 225 WP_010871693.1 DUF433 domain-containing protein Antitoxin
SYNGTI_RS02505 545352..545690 + 339 WP_010871694.1 DUF5615 family PIN-like protein Toxin
SYNGTI_RS02510 545693..546658 - 966 WP_010871695.1 carbon-nitrogen hydrolase family protein -
SYNGTI_RS02515 546655..547467 - 813 WP_014407074.1 urease accessory protein UreD -
SYNGTI_RS02520 547527..547976 - 450 WP_010871697.1 photosystem II protein PsbQ -
SYNGTI_RS02525 548338..549234 + 897 WP_010871698.1 prohibitin family protein -
SYNGTI_RS02530 549231..549803 - 573 WP_010871699.1 gamma carbonic anhydrase family protein -
SYNGTI_RS02535 550096..550431 + 336 WP_010871700.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Domain of unknown function DUF5615

(1-78)

Antitoxin

Protein of unknown function DUF433

(8-63)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12464.32 Da        Isoelectric Point: 4.2931

>T26177 WP_010871694.1 NC_017038:545352-545690 [Synechocystis sp. PCC 6803 substr. GT-I]
MNIWVDAQLPPTLADWLSSNFDLEASALRDLGLRDARDIEIFDAARVANSVIMTKDSDFVDLVCRLGIPPQIIWLTCGNV
TNRNLRRILSSTLPQALEKLQAGEIIIEISNS

Download         Length: 339 bp

>T26177 NC_017038:545352-545690 [Synechocystis sp. PCC 6803 substr. GT-I]
ATGAATATTTGGGTTGATGCTCAACTACCTCCAACATTGGCAGATTGGCTGTCGAGTAATTTTGATTTAGAGGCGTCAGC
TTTGAGGGATCTGGGATTACGGGATGCAAGAGACATTGAAATTTTTGATGCCGCACGAGTTGCCAACTCTGTAATCATGA
CAAAAGACAGCGACTTCGTTGATCTTGTATGTCGATTAGGAATACCACCTCAAATCATTTGGCTAACTTGCGGTAACGTT
ACGAATCGAAACTTACGTCGAATTCTCTCAAGTACTTTGCCACAGGCTCTGGAAAAACTGCAAGCAGGCGAAATTATCAT
AGAAATCAGCAACTCCTGA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8232.51 Da        Isoelectric Point: 4.6320

>AT26177 WP_010871693.1 NC_017038:545131-545355 [Synechocystis sp. PCC 6803 substr. GT-I]
MNSLLSRITQTPGQCGGRPCIRGMRIRVSDILEMLAENVSTSEILEDFPDLEMADIQACLVFAARRTDFSRLTA

Download         Length: 225 bp

>AT26177 NC_017038:545131-545355 [Synechocystis sp. PCC 6803 substr. GT-I]
ATGAATAGCTTACTGTCTCGCATTACCCAAACCCCCGGTCAGTGTGGTGGTCGTCCTTGTATTCGAGGGATGAGGATTCG
AGTGAGCGACATCCTAGAAATGTTAGCTGAGAATGTTAGCACCTCTGAGATTTTAGAGGACTTTCCAGACCTAGAAATGG
CCGATATTCAGGCTTGTCTAGTGTTTGCTGCACGGCGGACTGATTTTTCCCGGTTGACGGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References