Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3490643..3491296 Replicon chromosome
Accession NZ_CP107585
Organism Acinetobacter baumannii strain 1326527-1

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag OIO72_RS16770 Protein ID WP_025467596.1
Coordinates 3490643..3491032 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag OIO72_RS16775 Protein ID WP_001288210.1
Coordinates 3491039..3491296 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OIO72_RS16755 (OIO72_16760) 3485761..3487956 - 2196 WP_001158905.1 TRAP transporter large permease subunit -
OIO72_RS16760 (OIO72_16765) 3488144..3488710 - 567 WP_000651536.1 rhombosortase -
OIO72_RS16765 (OIO72_16770) 3488788..3489873 - 1086 WP_000049106.1 hypothetical protein -
OIO72_RS16770 (OIO72_16775) 3490643..3491032 - 390 WP_025467596.1 membrane protein Toxin
OIO72_RS16775 (OIO72_16780) 3491039..3491296 - 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
OIO72_RS16780 (OIO72_16785) 3491484..3492656 + 1173 WP_031961342.1 acyl-CoA dehydrogenase family protein -
OIO72_RS16785 (OIO72_16790) 3492705..3494195 - 1491 WP_000415133.1 NAD(P)/FAD-dependent oxidoreductase -
OIO72_RS16790 (OIO72_16795) 3494377..3494754 - 378 WP_001216380.1 50S ribosomal protein L17 -
OIO72_RS16795 (OIO72_16800) 3494773..3495780 - 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15609.84 Da        Isoelectric Point: 10.3816

>T261768 WP_025467596.1 NZ_CP107585:c3491032-3490643 [Acinetobacter baumannii]
MINHLNFQLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLH

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT261768 WP_001288210.1 NZ_CP107585:c3491296-3491039 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References