Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3486307..3486960 Replicon chromosome
Accession NZ_CP107581
Organism Acinetobacter baumannii strain 1326525-2

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag OIO86_RS16740 Protein ID WP_025467596.1
Coordinates 3486307..3486696 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag OIO86_RS16745 Protein ID WP_001288210.1
Coordinates 3486703..3486960 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OIO86_RS16725 (OIO86_16730) 3481425..3483620 - 2196 WP_001158905.1 TRAP transporter large permease subunit -
OIO86_RS16730 (OIO86_16735) 3483808..3484374 - 567 WP_000651536.1 rhombosortase -
OIO86_RS16735 (OIO86_16740) 3484452..3485537 - 1086 WP_000049106.1 hypothetical protein -
OIO86_RS16740 (OIO86_16745) 3486307..3486696 - 390 WP_025467596.1 membrane protein Toxin
OIO86_RS16745 (OIO86_16750) 3486703..3486960 - 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
OIO86_RS16750 (OIO86_16755) 3487148..3488320 + 1173 WP_031961342.1 acyl-CoA dehydrogenase family protein -
OIO86_RS16755 (OIO86_16760) 3488369..3489859 - 1491 WP_000415133.1 NAD(P)/FAD-dependent oxidoreductase -
OIO86_RS16760 (OIO86_16765) 3490041..3490418 - 378 WP_001216380.1 50S ribosomal protein L17 -
OIO86_RS16765 (OIO86_16770) 3490437..3491444 - 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15609.84 Da        Isoelectric Point: 10.3816

>T261763 WP_025467596.1 NZ_CP107581:c3486696-3486307 [Acinetobacter baumannii]
MINHLNFQLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLH

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT261763 WP_001288210.1 NZ_CP107581:c3486960-3486703 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References