Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 460301..460954 Replicon chromosome
Accession NZ_CP107577
Organism Acinetobacter baumannii strain 1326359

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag OIO45_RS02235 Protein ID WP_025467596.1
Coordinates 460565..460954 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag OIO45_RS02230 Protein ID WP_001288210.1
Coordinates 460301..460558 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OIO45_RS02210 (OIO45_02210) 455817..456824 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
OIO45_RS02215 (OIO45_02215) 456843..457220 + 378 WP_001216380.1 50S ribosomal protein L17 -
OIO45_RS02220 (OIO45_02220) 457402..458892 + 1491 WP_000415133.1 NAD(P)/FAD-dependent oxidoreductase -
OIO45_RS02225 (OIO45_02225) 458941..460113 - 1173 WP_031961342.1 acyl-CoA dehydrogenase family protein -
OIO45_RS02230 (OIO45_02230) 460301..460558 + 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
OIO45_RS02235 (OIO45_02235) 460565..460954 + 390 WP_025467596.1 membrane protein Toxin
OIO45_RS02240 (OIO45_02240) 461724..462809 + 1086 WP_000049106.1 hypothetical protein -
OIO45_RS02245 (OIO45_02245) 462887..463453 + 567 WP_000651536.1 rhombosortase -
OIO45_RS02250 (OIO45_02250) 463641..465836 + 2196 WP_001158905.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15609.84 Da        Isoelectric Point: 10.3816

>T261759 WP_025467596.1 NZ_CP107577:460565-460954 [Acinetobacter baumannii]
MINHLNFQLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLH

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT261759 WP_001288210.1 NZ_CP107577:460301-460558 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References