261758

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 3734027..3735066 Replicon chromosome
Accession NZ_CP107576
Organism Pseudomonas asiatica strain JP233

Toxin (Protein)


Gene name PP_4152 Uniprot ID A0A2N5BP56
Locus tag jpw_RS17300 Protein ID WP_015271072.1
Coordinates 3734491..3735066 (+) Length 192 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID A0A2N5BP88
Locus tag jpw_RS17295 Protein ID WP_015271071.1
Coordinates 3734027..3734494 (+) Length 156 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
jpw_RS17275 (jpw_17275) 3730091..3731110 + 1020 WP_013973404.1 ABC transporter permease -
jpw_RS17280 (jpw_17280) 3731112..3732725 + 1614 WP_100413749.1 ABC transporter ATP-binding protein -
jpw_RS17285 (jpw_17285) 3733183..3733425 + 243 WP_015271069.1 hypothetical protein -
jpw_RS17290 (jpw_17290) 3733582..3733845 + 264 WP_015271070.1 DUF3077 domain-containing protein -
jpw_RS17295 (jpw_17295) 3734027..3734494 + 468 WP_015271071.1 helix-turn-helix domain-containing protein Antitoxin
jpw_RS17300 (jpw_17300) 3734491..3735066 + 576 WP_015271072.1 PIN domain-containing protein Toxin
jpw_RS17305 (jpw_17305) 3735281..3738211 + 2931 WP_085720481.1 aminotransferase -
jpw_RS17310 (jpw_17310) 3738383..3739288 + 906 WP_013973410.1 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(9-115)

Antitoxin

SinI-like, DNA-binding domain

(84-129)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21970.23 Da        Isoelectric Point: 5.0798

>T261758 WP_015271072.1 NZ_CP107576:3734491-3735066 [Pseudomonas asiatica]
MKHSPFTAIYDANVLYPAPLRDFLMNLALTGIYRARWSTKIHDEWKRNLLLNRPDLTLEQVDRTSRRMDAAVPDALVTDY
ESLVEGLDLPDKDDRHVLAAAIKCNASVIVTFNLKDFPETALDVFDIEPLHPDDFIADLWDLDKAAVLEAAQRQRMSLKN
PPHSVQQYLDRLLQQKLPESVKLLSEFKFLL

Download         Length: 576 bp

Antitoxin


Download         Length: 156 a.a.        Molecular weight: 17366.86 Da        Isoelectric Point: 5.3408

>AT261758 WP_015271071.1 NZ_CP107576:3734027-3734494 [Pseudomonas asiatica]
MTTADLSRKMLPDEKEIAVAVESSRTLAAFLSTKSDTQRIELLNEENQRQVVEVPTFALRLFGEILSELALGNSVKVVPI
HAELTTQEAADLLNVSRPYLVKLLDESVIPHTKTGRHRRVKFSDLVAYKDKRDEVSRAAMDALAAEAQELRMGYE

Download         Length: 468 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2N5BP56

Antitoxin

Source ID Structure
AlphaFold DB A0A2N5BP88

References