Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /RES-TIGR02293 |
| Location | 3485281..3486164 | Replicon | chromosome |
| Accession | NZ_CP107576 | ||
| Organism | Pseudomonas asiatica strain JP233 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | A0A0C1HTG7 |
| Locus tag | jpw_RS16100 | Protein ID | WP_015270851.1 |
| Coordinates | 3485281..3485718 (-) | Length | 146 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | F8G488 |
| Locus tag | jpw_RS16105 | Protein ID | WP_013973163.1 |
| Coordinates | 3485715..3486164 (-) | Length | 150 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| jpw_RS16080 (jpw_16080) | 3480509..3481573 | + | 1065 | WP_015270847.1 | TerC family protein | - |
| jpw_RS16085 (jpw_16085) | 3481651..3482880 | - | 1230 | WP_015270848.1 | acyl-CoA dehydrogenase | - |
| jpw_RS16090 (jpw_16090) | 3483021..3483947 | + | 927 | WP_015270849.1 | LysR family transcriptional regulator | - |
| jpw_RS16095 (jpw_16095) | 3484119..3485273 | + | 1155 | WP_054572084.1 | aminotransferase class V-fold PLP-dependent enzyme | - |
| jpw_RS16100 (jpw_16100) | 3485281..3485718 | - | 438 | WP_015270851.1 | RES family NAD+ phosphorylase | Toxin |
| jpw_RS16105 (jpw_16105) | 3485715..3486164 | - | 450 | WP_013973163.1 | DUF2384 domain-containing protein | Antitoxin |
| jpw_RS16110 (jpw_16110) | 3486263..3486916 | - | 654 | WP_061304057.1 | oxygen-insensitive NAD(P)H nitroreductase | - |
| jpw_RS16115 (jpw_16115) | 3487021..3487944 | + | 924 | WP_054572087.1 | LysR family transcriptional regulator | - |
| jpw_RS16120 (jpw_16120) | 3487992..3488822 | + | 831 | WP_264209570.1 | AraC family transcriptional regulator | - |
| jpw_RS16125 (jpw_16125) | 3488873..3489457 | + | 585 | WP_054572088.1 | LysE family translocator | - |
| jpw_RS16130 (jpw_16130) | 3489597..3490796 | - | 1200 | WP_054572089.1 | sugar transporter | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 146 a.a. Molecular weight: 15969.19 Da Isoelectric Point: 5.1199
>T261757 WP_015270851.1 NZ_CP107576:c3485718-3485281 [Pseudomonas asiatica]
VILWRISAYADLSGTGGLRVSGRWHQAGRPVVYAATSPAGAMLEVLVHLEIDPEDFPTTMRLLRIELPDTVSQAQLPALQ
PGWSSQTELTRGLGNRFLDECSALLLPVPSAIMPSTTNYLFNPRHPQANSARLEVEDFTPDSRLF
VILWRISAYADLSGTGGLRVSGRWHQAGRPVVYAATSPAGAMLEVLVHLEIDPEDFPTTMRLLRIELPDTVSQAQLPALQ
PGWSSQTELTRGLGNRFLDECSALLLPVPSAIMPSTTNYLFNPRHPQANSARLEVEDFTPDSRLF
Download Length: 438 bp
Antitoxin
Download Length: 150 a.a. Molecular weight: 17004.59 Da Isoelectric Point: 6.3405
>AT261757 WP_013973163.1 NZ_CP107576:c3486164-3485715 [Pseudomonas asiatica]
MLAEVLRDNGYHEYRARLHALLEIPELASDFEIHTRITHGFAATWLVKLTELGVFTPVERDQIIPLRTLKTRIERDQPLT
VEESDRLFRSAHITAMAEAVFGEAGKAKRWLSKPKERFSGLTPMQMLTTQQGTTQVEEMLLQIAEGFGL
MLAEVLRDNGYHEYRARLHALLEIPELASDFEIHTRITHGFAATWLVKLTELGVFTPVERDQIIPLRTLKTRIERDQPLT
VEESDRLFRSAHITAMAEAVFGEAGKAKRWLSKPKERFSGLTPMQMLTTQQGTTQVEEMLLQIAEGFGL
Download Length: 450 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A0C1HTG7 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | F8G488 |