261756

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 2250993..2251509 Replicon chromosome
Accession NZ_CP107576
Organism Pseudomonas asiatica strain JP233

Toxin (Protein)


Gene name relE Uniprot ID F8G1E7
Locus tag jpw_RS10465 Protein ID WP_003259987.1
Coordinates 2251228..2251509 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID F8G1E6
Locus tag jpw_RS10460 Protein ID WP_013972043.1
Coordinates 2250993..2251238 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
jpw_RS10440 (jpw_10440) 2246405..2246884 - 480 WP_137137396.1 transposase -
jpw_RS10445 (jpw_10445) 2247141..2247683 - 543 WP_015269935.1 WYL domain-containing protein -
jpw_RS10450 (jpw_10450) 2248419..2249612 + 1194 WP_015269936.1 MFS transporter -
jpw_RS10455 (jpw_10455) 2249643..2250749 + 1107 WP_054572951.1 alkene reductase -
jpw_RS10460 (jpw_10460) 2250993..2251238 + 246 WP_013972043.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
jpw_RS10465 (jpw_10465) 2251228..2251509 + 282 WP_003259987.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
jpw_RS10470 (jpw_10470) 2251525..2252157 - 633 WP_015269938.1 BRCT domain-containing protein -
jpw_RS10475 (jpw_10475) 2252174..2252569 - 396 WP_023662326.1 hypothetical protein -
jpw_RS10480 (jpw_10480) 2252658..2253566 - 909 WP_013972045.1 LysR family transcriptional regulator -
jpw_RS10485 (jpw_10485) 2253858..2255162 + 1305 WP_013972046.1 MFS transporter -
jpw_RS10490 (jpw_10490) 2255193..2256434 + 1242 WP_015269941.1 Zn-dependent hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(10-76)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10909.78 Da        Isoelectric Point: 10.7594

>T261756 WP_003259987.1 NZ_CP107576:2251228-2251509 [Pseudomonas asiatica]
MTYKLEFLPSALKEWGKLGHTVREQIKKKLAERLQSPKVQADALRDLPNHYKIKLKASGYRLVYRVEDERIVVVVVSVGK
RERSEVYRSAQKR

Download         Length: 282 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8779.21 Da        Isoelectric Point: 4.3611

>AT261756 WP_013972043.1 NZ_CP107576:2250993-2251238 [Pseudomonas asiatica]
MQNIFADVAVSVSELKKNPSAVMTGAAGMPVAVLNHNRVMGYMVPAELYEAMMERLEDLELSELAKSRLGEKGVPVSLDD
L

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB F8G1E7

Antitoxin

Source ID Structure
AlphaFold DB F8G1E6

References