Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09907-MazE
Location 609125..609702 Replicon plasmid pJL.02bL
Accession NZ_CP107574
Organism Pantoea dispersa strain JL.02bL

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag OF384_RS22315 Protein ID WP_058781048.1
Coordinates 609370..609702 (+) Length 111 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID A0A8E1V6C0
Locus tag OF384_RS22310 Protein ID WP_058770344.1
Coordinates 609125..609370 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OF384_RS22290 (OF384_22290) 604487..605440 + 954 WP_264251862.1 carbohydrate kinase family protein -
OF384_RS22295 (OF384_22295) 605444..606526 + 1083 WP_058776100.1 sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC -
OF384_RS22300 (OF384_22300) 606646..608055 - 1410 WP_058758997.1 MFS transporter -
OF384_RS22305 (OF384_22305) 608171..609025 + 855 WP_058770343.1 helix-turn-helix transcriptional regulator -
OF384_RS22310 (OF384_22310) 609125..609370 + 246 WP_058770344.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
OF384_RS22315 (OF384_22315) 609370..609702 + 333 WP_058781048.1 endoribonuclease MazF Toxin
OF384_RS22320 (OF384_22320) 609808..609981 + 174 WP_021508895.1 hypothetical protein -
OF384_RS22325 (OF384_22325) 610011..610358 + 348 WP_021508894.1 hypothetical protein -
OF384_RS22330 (OF384_22330) 610398..611591 - 1194 WP_021508893.1 zinc-dependent alcohol dehydrogenase -
OF384_RS22335 (OF384_22335) 611855..612562 + 708 WP_021508892.1 phage antirepressor KilAC domain-containing protein -
OF384_RS22340 (OF384_22340) 612597..612812 - 216 WP_021508891.1 hypothetical protein -
OF384_RS22345 (OF384_22345) 612954..614135 - 1182 WP_264251863.1 FAD-binding oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - iroN 1..696693 696693


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(9-107)

Antitoxin

SpoVT-AbrB domain

(7-49)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 11995.82 Da        Isoelectric Point: 7.8855

>T261755 WP_058781048.1 NZ_CP107574:609370-609702 [Pantoea dispersa]
MVSRFVPDAGDLIWLDFDPTLGHEQGGHRPAVVLSPFAYNNKVGMLLCVPCTTQVKGYPFEVSLTGSRDSVALADQVTSI
DWRARKVVKKSHVTADELSEIRAKAKALIG

Download         Length: 333 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8955.25 Da        Isoelectric Point: 4.5580

>AT261755 WP_058770344.1 NZ_CP107574:609125-609370 [Pantoea dispersa]
MTTVTLKKWGNSPSIRIPSSVMQSASLSVDDKLELSVEDGKLILVPLREKVYSLDALLDEITDDNVHDKIDFGPSVGKER
I

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References