Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 515694..516400 Replicon plasmid pJL.02bL
Accession NZ_CP107574
Organism Pantoea dispersa strain JL.02bL

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OF384_RS21835 Protein ID WP_264251825.1
Coordinates 516122..516400 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OF384_RS21830 Protein ID WP_211726866.1
Coordinates 515694..516020 (-) Length 109 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OF384_RS21810 (OF384_21810) 511321..512355 - 1035 WP_264251824.1 aldehyde reductase -
OF384_RS21815 (OF384_21815) 512464..513396 + 933 WP_021508995.1 AraC family transcriptional regulator -
OF384_RS21820 (OF384_21820) 513425..514459 - 1035 WP_021508994.1 L-glyceraldehyde 3-phosphate reductase -
OF384_RS21825 (OF384_21825) 514629..515528 + 900 WP_125311491.1 LysR family transcriptional regulator -
OF384_RS21830 (OF384_21830) 515694..516020 - 327 WP_211726866.1 helix-turn-helix domain-containing protein Antitoxin
OF384_RS21835 (OF384_21835) 516122..516400 - 279 WP_264251825.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OF384_RS21840 (OF384_21840) 516704..516994 + 291 WP_021508990.1 hypothetical protein -
OF384_RS21845 (OF384_21845) 517020..518447 - 1428 WP_264251826.1 trehalose-6-phosphate synthase -
OF384_RS21850 (OF384_21850) 518619..519482 - 864 WP_132463164.1 substrate-binding domain-containing protein -
OF384_RS21855 (OF384_21855) 519717..520412 + 696 WP_058775966.1 hypothetical protein -
OF384_RS21860 (OF384_21860) 520510..521040 + 531 WP_021508986.1 outer membrane lipoprotein Blc -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - iroN 1..696693 696693


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(1-81)

Antitoxin

Cro/C1-type helix-turn-helix domain

(53-95)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 9952.67 Da        Isoelectric Point: 10.7392

>T261753 WP_264251825.1 NZ_CP107574:c516400-516122 [Pantoea dispersa]
MAIYVLKPFDRNFKGDMIADIKLCLAARELIAGQYEASLGGGVYKKRIPLGAGKSGGARAIVAFKSQKHLFFVNGYAKST
TKSGIREINTRG

Download         Length: 279 bp

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 12278.27 Da        Isoelectric Point: 7.3214

>AT261753 WP_211726866.1 NZ_CP107574:c516020-515694 [Pantoea dispersa]
MVDHLKDLQEIAHDFNPLGVVSDELTEKIDSRVRLRELRTSLPVLQLMSGEAIRELRERHGLSQAMLAAYIGLSPATVVK
WEREEKKPNGAALRLLNLIDRKGLEVLR

Download         Length: 327 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References