Detailed information of TA system TA026175

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ParST/RES-Xre
• Location: 3073688..3074664
• Replicon: chromosome
• Accession: NC_017033
• Organism: Frateuria aurantia DSM 6220

Toxin (Protein)

• Gene name: ParT
• Uniprot ID: H8L134
• Locus tag: FRAAU_RS14115
• Protein ID: WP_014404192.1
• Coordinates: 3073688..3074167 (-)
• Length: 160 a.a.

Antitoxin (Protein)

• Gene name: ParS
• Uniprot ID: H8L135
• Locus tag: FRAAU_RS17445
• Protein ID: WP_014404193.1
• Coordinates: 3074164..3074664 (-)
• Length: 167 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FRAAU_RS14095	3069444..3069821	-	378	WP_014404188.1	DUF202 domain-containing protein	-
FRAAU_RS14100	3069818..3071188	-	1371	WP_014404189.1	FAD/NAD(P)-binding protein	-
FRAAU_RS14105	3071339..3072568	-	1230	WP_014404190.1	spore maturation protein	-
FRAAU_RS14110	3072820..3073386	+	567	WP_014404191.1	single-stranded DNA-binding protein	-
FRAAU_RS14115	3073688..3074167	-	480	WP_014404192.1	RES family NAD+ phosphorylase	Toxin
FRAAU_RS17445	3074164..3074664	-	501	WP_014404193.1	DUF2384 domain-containing protein	Antitoxin
FRAAU_RS14125	3075091..3077382	-	2292	WP_041270609.1	penicillin-binding protein 1C	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (5-152)

Antitoxin

• Antitoxin Xre-like, helix-turn-helix domain (38-96)

Sequences

Toxin

Protein

• Length: 160 a.a.
• Molecular weight: 17365.86 Da
• Isoelectric Point: 7.1655

>T26175 WP_014404192.1 NC_017033:c3074167-3073688 [Frateuria aurantia DSM 6220]
VTTSLWRLGTDTPDYGADDLSGIGAKITGGRWNRKGLPVVYTAATIALATLETVVHLGAGSLPLNRCLVRIDVPDDIWNA
ARPFPTTGLIGWDALPAGLVSLDFGDAWLQSRATVLQIVPSIVVPEEWNVLLNPAHPDMQRITATRIRRFTYDSRFRSS

Nucleotide

• Length: 480 bp

>T26175 NC_017033:c3074167-3073688 [Frateuria aurantia DSM 6220]
GTGACCACTTCGCTCTGGCGTCTGGGTACCGATACGCCAGATTACGGCGCTGACGATCTGAGTGGCATAGGTGCGAAAAT
CACCGGCGGGCGGTGGAACAGAAAGGGCCTGCCGGTCGTCTACACGGCGGCCACGATCGCTTTGGCGACGCTGGAGACCG
TGGTCCACCTCGGCGCGGGCAGCCTTCCCTTGAATCGTTGCCTGGTCCGCATCGATGTGCCGGACGATATATGGAACGCA
GCGCGCCCGTTCCCCACCACGGGCTTGATCGGGTGGGATGCCTTGCCGGCGGGGTTGGTATCACTCGACTTTGGTGATGC
CTGGCTGCAGTCCCGGGCCACGGTGCTCCAGATCGTTCCTTCCATCGTGGTGCCTGAGGAATGGAATGTGCTGCTAAACC
CGGCACACCCTGACATGCAGCGGATCACTGCGACCAGAATTCGGAGATTCACCTACGACAGCCGATTTCGGAGCAGCTGA

Antitoxin

Protein

• Length: 167 a.a.
• Molecular weight: 18168.80 Da
• Isoelectric Point: 9.5710

>AT26175 WP_014404193.1 NC_017033:c3074664-3074164 [Frateuria aurantia DSM 6220]
MKDNLTRQHSVAKTPKVSGHDKTTIVSCRDIYRAAPIERVRLVENGIPARDLLGLATSMKVQYQRLFSTLGLSRTTVTRK
VREHEPLNTADSERVLGMMQLVGQVEDIVSQSGDPQGFDAPAWLAQWLERPLPALEGKTPASYMGTIPGQQLVSSLLAQA
QSGAFA

Nucleotide

• Length: 501 bp

>AT26175 NC_017033:c3074664-3074164 [Frateuria aurantia DSM 6220]
ATGAAAGACAACCTGACGAGGCAGCACAGCGTCGCAAAAACGCCCAAGGTCAGTGGTCACGACAAAACAACCATCGTGTC
ATGCCGGGATATTTATCGCGCAGCGCCGATCGAGCGGGTTCGTCTCGTCGAGAACGGCATTCCTGCCAGGGACCTGCTGG
GTCTCGCGACTTCGATGAAGGTGCAGTATCAGCGCCTGTTCTCGACGCTCGGTCTGTCCCGCACCACGGTCACCCGAAAG
GTCAGGGAGCATGAGCCACTCAATACGGCCGACAGCGAGCGTGTGCTGGGGATGATGCAACTGGTCGGGCAGGTGGAAGA
CATCGTTTCGCAGAGCGGCGATCCGCAAGGTTTCGATGCGCCCGCATGGCTGGCCCAATGGCTGGAACGCCCACTCCCGG
CACTTGAGGGCAAGACGCCTGCCAGCTACATGGGCACCATTCCGGGTCAGCAACTCGTGTCCTCCCTGCTTGCCCAGGCG
CAGTCCGGGGCTTTTGCGTGA

Structures

Toxin

• AlphaFold DB: H8L134

Antitoxin

• AlphaFold DB: H8L135