Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/Fic(toxin)
Location 2921121..2921686 Replicon chromosome
Accession NZ_CP107567
Organism Streptomyces peucetius strain NA0869

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag OGH68_RS13340 Protein ID WP_264243761.1
Coordinates 2921121..2921489 (-) Length 123 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag OGH68_RS13345 Protein ID WP_159691605.1
Coordinates 2921489..2921686 (-) Length 66 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OGH68_RS13325 (OGH68_13325) 2916614..2917402 - 789 WP_264243755.1 S16 family serine protease -
OGH68_RS13330 (OGH68_13330) 2918261..2918902 - 642 WP_264243757.1 helix-turn-helix domain-containing protein -
OGH68_RS13335 (OGH68_13335) 2919179..2920963 - 1785 WP_264243759.1 DEAD/DEAH box helicase -
OGH68_RS13340 (OGH68_13340) 2921121..2921489 - 369 WP_264243761.1 Fic family protein Toxin
OGH68_RS13345 (OGH68_13345) 2921489..2921686 - 198 WP_159691605.1 Arc family DNA-binding protein Antitoxin
OGH68_RS13350 (OGH68_13350) 2921720..2923186 - 1467 WP_264243763.1 MFS transporter -
OGH68_RS13355 (OGH68_13355) 2923486..2923845 + 360 WP_264243765.1 hypothetical protein -
OGH68_RS13360 (OGH68_13360) 2923865..2926159 + 2295 WP_264243767.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Death on curing protein

(12-117)

Antitoxin

Arc-like DNA binding domain

(5-33)


Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 13743.66 Da        Isoelectric Point: 4.8500

>T261743 WP_264243761.1 NZ_CP107567:c2921489-2921121 [Streptomyces peucetius]
MNYLTLPELLKLAERLGAEEVRDYGLLDSALARPQSSVFGQDAYPDIWQKAAALMESLARNHALVDGNKRIAWYATWVFL
HMNGHRLSPGFDVDEAEQFVLNVCQGLLDVPKTAEQLPRFAQ

Download         Length: 369 bp

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 7351.17 Da        Isoelectric Point: 5.0762

>AT261743 WP_159691605.1 NZ_CP107567:c2921686-2921489 [Streptomyces peucetius]
MAGLNLRFTEEELNALRERAEAEGRSMQSFAHDAVITAINEHSRLFNEAADHVLKASEELNRRLA

Download         Length: 198 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References