Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09812-MazE
Location 3368868..3369459 Replicon chromosome
Accession NZ_CP107558
Organism Methylocystis sp. MJC1

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag OGR47_RS16200 Protein ID WP_165055102.1
Coordinates 3369127..3369459 (+) Length 111 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag OGR47_RS16195 Protein ID WP_165055104.1
Coordinates 3368868..3369125 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OGR47_RS16170 (OGR47_16170) 3364360..3364608 + 249 WP_165055109.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
OGR47_RS16175 (OGR47_16175) 3364575..3364988 + 414 WP_246729810.1 type II toxin-antitoxin system VapC family toxin -
OGR47_RS16180 (OGR47_16180) 3365103..3365750 + 648 WP_165055108.1 preprotein translocase subunit SecG -
OGR47_RS16185 (OGR47_16185) 3365861..3367489 + 1629 WP_165055106.1 CTP synthase -
OGR47_RS16190 (OGR47_16190) 3368335..3368799 + 465 WP_165055105.1 diadenylate cyclase -
OGR47_RS16195 (OGR47_16195) 3368868..3369125 + 258 WP_165055104.1 antitoxin Antitoxin
OGR47_RS16200 (OGR47_16200) 3369127..3369459 + 333 WP_165055102.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
OGR47_RS16205 (OGR47_16205) 3369487..3369711 - 225 WP_246729813.1 ribbon-helix-helix domain-containing protein -
OGR47_RS16210 (OGR47_16210) 3369789..3369971 - 183 WP_165055099.1 DUF4169 family protein -
OGR47_RS16215 (OGR47_16215) 3369971..3370537 - 567 WP_165055097.1 ClpXP protease specificity-enhancing factor SspB -
OGR47_RS16225 (OGR47_16225) 3371237..3372121 + 885 WP_165055096.1 succinate--CoA ligase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(2-109)

Antitoxin

Antitoxin PemI-like

(5-84)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 11630.43 Da        Isoelectric Point: 7.8642

>T261739 WP_165055102.1 NZ_CP107558:3369127-3369459 [Methylocystis sp. MJC1]
MERGDIYLVSLDPTSGHEQRGARPVLIVSATAFNKITKTPIVLPITSGGNFARTAGFAVSLMGAGTQTTGVIRCDQPRAL
DLGARHARKLECAPPEIVDEALAKLAAIFE

Download         Length: 333 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 8931.29 Da        Isoelectric Point: 4.7204

>AT261739 WP_165055104.1 NZ_CP107558:3368868-3369125 [Methylocystis sp. MJC1]
MHTTSLRKVGGSVMLAVPPAILDLLDLKAGATVGVSVEDGKLVIAPTTKSRYKLAELLAQCDASAEPSEEDRAWLGDKPQ
GSELL

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References