Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09812-MazE
Location 3368868..3369459 Replicon chromosome
Accession NZ_CP107558
Organism Methylocystis sp. MJC1

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag OGR47_RS16200 Protein ID WP_165055102.1
Coordinates 3369127..3369459 (+) Length 111 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag OGR47_RS16195 Protein ID WP_165055104.1
Coordinates 3368868..3369125 (+) Length 86 a.a.

Genomic Context

OGR47_RS16170OGR47_RS16175OGR47_RS16180OGR47_RS16185OGR47_RS16190OGR47_RS16195OGR47_RS16200OGR47_RS16225OGR47_RS16205OGR47_RS16210OGR47_RS16215
Location: 3364360..3364608 (249 bp)
Type: Others
Protein ID: WP_165055109.1
Location: 3364575..3364988 (414 bp)
Type: Others
Protein ID: WP_246729810.1
Location: 3365103..3365750 (648 bp)
Type: Others
Protein ID: WP_165055108.1
Location: 3365861..3367489 (1629 bp)
Type: Others
Protein ID: WP_165055106.1
Location: 3368335..3368799 (465 bp)
Type: Others
Protein ID: WP_165055105.1
Location: 3368868..3369125 (258 bp)
Type: Antitoxin
Protein ID: WP_165055104.1
Location: 3369127..3369459 (333 bp)
Type: Toxin
Protein ID: WP_165055102.1
Location: 3371237..3372121 (885 bp)
Type: Others
Protein ID: WP_165055096.1
Location: 3369487..3369711 (225 bp)
Type: Others
Protein ID: WP_246729813.1
Location: 3369789..3369971 (183 bp)
Type: Others
Protein ID: WP_165055099.1
Location: 3369971..3370537 (567 bp)
Type: Others
Protein ID: WP_165055097.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
OGR47_RS16170 (OGR47_16170)3364360..3364608+249WP_165055109.1type II toxin-antitoxin system Phd/YefM family antitoxin-
OGR47_RS16175 (OGR47_16175)3364575..3364988+414WP_246729810.1type II toxin-antitoxin system VapC family toxin-
OGR47_RS16180 (OGR47_16180)3365103..3365750+648WP_165055108.1preprotein translocase subunit SecG-
OGR47_RS16185 (OGR47_16185)3365861..3367489+1629WP_165055106.1CTP synthase-
OGR47_RS16190 (OGR47_16190)3368335..3368799+465WP_165055105.1diadenylate cyclase-
OGR47_RS16195 (OGR47_16195)3368868..3369125+258WP_165055104.1antitoxinAntitoxin
OGR47_RS16200 (OGR47_16200)3369127..3369459+333WP_165055102.1type II toxin-antitoxin system PemK/MazF family toxinToxin
OGR47_RS16205 (OGR47_16205)3369487..3369711-225WP_246729813.1ribbon-helix-helix domain-containing protein-
OGR47_RS16210 (OGR47_16210)3369789..3369971-183WP_165055099.1DUF4169 family protein-
OGR47_RS16215 (OGR47_16215)3369971..3370537-567WP_165055097.1ClpXP protease specificity-enhancing factor SspB-
OGR47_RS16225 (OGR47_16225)3371237..3372121+885WP_165055096.1succinate--CoA ligase subunit alpha-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(2-109)

Antitoxin

Antitoxin PemI-like

(5-84)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 11630.43 Da        Isoelectric Point: 7.8642

>T261739 WP_165055102.1 NZ_CP107558:3369127-3369459 [Methylocystis sp. MJC1]
MERGDIYLVSLDPTSGHEQRGARPVLIVSATAFNKITKTPIVLPITSGGNFARTAGFAVSLMGAGTQTTGVIRCDQPRAL
DLGARHARKLECAPPEIVDEALAKLAAIFE

Download         Length: 333 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 8931.29 Da        Isoelectric Point: 4.7204

>AT261739 WP_165055104.1 NZ_CP107558:3368868-3369125 [Methylocystis sp. MJC1]
MHTTSLRKVGGSVMLAVPPAILDLLDLKAGATVGVSVEDGKLVIAPTTKSRYKLAELLAQCDASAEPSEEDRAWLGDKPQ
GSELL

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References